| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Visium Asset Management, LP | 1,206,000 | 6,344,000 | 34.42% | ||
| 2 | VHCP Management, LLC | 669,921 | 3,524,000 | 19.12% | ||
| 3 | BAKER BROS. ADVISORS LP | 500,000 | 2,630,000 | 14.27% | ||
| 4 | Lombard Odier Asset Management (USA) Corp | 400,000 | 2,104,000 | 11.41% | ||
| 5 | RTW INVESTMENTS, LP | 209,333 | 1,101,000 | 5.97% | ||
| 6 | ROYCE & ASSOCIATES LP | 189,288 | 996,000 | 5.40% | ||
| 7 | MILLENNIUM MANAGEMENT LLC | 123,889 | 652,000 | 3.54% | ||
| 8 | VANGUARD GROUP INC | 86,421 | 455,000 | 2.47% | ||
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 47,750 | 251,000 | 1.36% | ||
| 10 | GOLDMAN SACHS GROUP INC | 22,609 | 119,000 | 0.65% | ||
| 11 | BlackRock Fund Advisors | 15,408 | 81,000 | 0.44% | ||
| 12 | A.R.T. Advisors, LLC | 13,585 | 71,000 | 0.39% | ||
| 13 | MORGAN STANLEY | 5,322 | 28,000 | 0.15% | ||
| 14 | CITIGROUP INC | 5,000 | 26,000 | 0.14% | ||
| 15 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 3,000 | 16,000 | 0.09% | ||
| 16 | DIMENSIONAL FUND ADVISORS LP | 2,200 | 12,000 | 0.07% | ||
| 17 | ADVANTAGE INVESTMENT MANAGEMENT, LLC | 1,450 | 8,000 | 0.04% | ||
| 18 | BlackRock Investment Management, LLC | 1,573 | 8,000 | 0.04% | ||
| 19 | DEUTSCHE BANK AG\ | 1,000 | 5,000 | 0.03% | ||
| 20 | UBS Group AG | 354 | 2,000 | 0.01% | ||
| 21 | ROYAL BANK OF CANADA | 63 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
