| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | VHCP Management, LLC | 1,269,921 | 10,896,000 | 15.13% | ||
| 2 | Visium Asset Management, LP | 1,136,000 | 9,747,000 | 13.53% | ||
| 3 | Invesco Ltd. | 1,075,000 | 9,223,000 | 12.81% | ||
| 4 | ARMISTICE CAPITAL, LLC | 850,000 | 7,293,000 | 10.13% | ||
| 5 | SABBY MANAGEMENT, LLC | 725,000 | 6,221,000 | 8.64% | ||
| 6 | Cormorant Asset Management, LP | 666,666 | 5,720,000 | 7.94% | ||
| 7 | Lombard Odier Asset Management (USA) Corp | 516,590 | 4,433,000 | 6.16% | ||
| 8 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 300,000 | 2,574,000 | 3.57% | ||
| 9 | VANGUARD GROUP INC | 295,963 | 2,539,000 | 3.53% | ||
| 10 | ROYCE & ASSOCIATES LP | 267,133 | 2,292,000 | 3.18% | ||
| 11 | RTW INVESTMENTS, LP | 209,333 | 1,796,000 | 2.49% | ||
| 12 | RENAISSANCE TECHNOLOGIES LLC | 183,861 | 1,578,000 | 2.19% | ||
| 13 | AMERIPRISE FINANCIAL INC | 125,800 | 1,079,000 | 1.50% | ||
| 14 | GEODE CAPITAL MANAGEMENT, LLC | 85,157 | 730,000 | 1.01% | ||
| 15 | DAFNA Capital Management LLC | 85,000 | 729,000 | 1.01% | ||
| 16 | BANK OF AMERICA CORP /DE/ | 83,106 | 713,000 | 0.99% | ||
| 17 | J. Goldman & Co LP | 74,999 | 643,000 | 0.89% | ||
| 18 | DIMENSIONAL FUND ADVISORS LP | 66,166 | 568,000 | 0.79% | ||
| 19 | MILLENNIUM MANAGEMENT LLC | 53,205 | 456,000 | 0.63% | ||
| 20 | DEUTSCHE BANK AG\ | 44,975 | 385,000 | 0.53% | ||
| 21 | BlackRock Fund Advisors | 41,041 | 352,000 | 0.49% | ||
| 22 | JPMORGAN CHASE & CO | 35,100 | 301,000 | 0.42% | ||
| 23 | P.A.W. CAPITAL CORP | 35,000 | 300,000 | 0.42% | ||
| 24 | EDMOND DE ROTHSCHILD (SUISSE) S.A. | 31,475 | 270,000 | 0.37% | ||
| 25 | EDMOND DE ROTHSCHILD HOLDING S.A. | 31,475 | 270,000 | 0.37% | ||
| 26 | GOLDMAN SACHS GROUP INC | 21,309 | 183,000 | 0.25% | ||
| 27 | Geduld E E | 20,000 | 172,000 | 0.24% | ||
| 28 | NORTHERN TRUST CORP | 18,727 | 161,000 | 0.22% | ||
| 29 | STATE STREET CORP | 12,600 | 108,000 | 0.15% | ||
| 30 | A.R.T. Advisors, LLC | 11,030 | 94,000 | 0.13% | ||
| 31 | LEVIN CAPITAL STRATEGIES, L.P. | 10,329 | 89,000 | 0.12% | ||
| 32 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 3,715 | 32,000 | 0.04% | ||
| 33 | BlackRock Investment Management, LLC | 2,540 | 22,000 | 0.03% | ||
| 34 | BlackRock Institutional Trust Company, N.A. | 1,949 | 17,000 | 0.02% | ||
| 35 | MORGAN STANLEY | 1,400 | 12,000 | 0.02% | ||
| 36 | Walleye Trading LLC | 1,400 | 12,000 | 0.02% | ||
| 37 | ADVANTAGE INVESTMENT MANAGEMENT, LLC | 1,450 | 12,000 | 0.02% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
