| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Invesco Ltd. | 1,075,000 | 13,900,000 | 11.72% | ||
| 2 | Visium Asset Management, LP | 977,768 | 12,643,000 | 10.66% | ||
| 3 | VHCP Management, LLC | 849,921 | 10,989,000 | 9.27% | ||
| 4 | ROYCE & ASSOCIATES LP | 820,223 | 10,605,000 | 8.94% | ||
| 5 | Cormorant Asset Management, LP | 666,666 | 8,620,000 | 7.27% | ||
| 6 | GILDER GAGNON HOWE & CO LLC | 502,675 | 6,500,000 | 5.48% | ||
| 7 | VHCP MANAGEMENT II, LLC | 420,000 | 5,431,000 | 4.58% | ||
| 8 | VANGUARD GROUP INC | 415,661 | 5,375,000 | 4.53% | ||
| 9 | Informed Momentum Co LLC | 402,073 | 5,199,000 | 4.38% | ||
| 10 | FORESITE CAPITAL MANAGEMENT III, LLC | 330,000 | 4,267,000 | 3.60% | ||
| 11 | DIMENSIONAL FUND ADVISORS LP | 271,272 | 3,508,000 | 2.96% | ||
| 12 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 243,830 | 3,153,000 | 2.66% | ||
| 13 | Carlson Capital, L.P. | 229,698 | 2,970,000 | 2.50% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 221,662 | 2,866,000 | 2.42% | ||
| 15 | RTW INVESTMENTS, LP | 216,414 | 2,798,000 | 2.36% | ||
| 16 | AMERIPRISE FINANCIAL INC | 213,676 | 2,763,000 | 2.33% | ||
| 17 | Lombard Odier Asset Management (USA) Corp | 210,668 | 2,724,000 | 2.30% | ||
| 18 | RENAISSANCE TECHNOLOGIES LLC | 179,200 | 2,317,000 | 1.95% | ||
| 19 | SABBY MANAGEMENT, LLC | 152,221 | 1,968,000 | 1.66% | ||
| 20 | RUSSELL FRANK CO/ | 97,583 | 1,265,000 | 1.07% | ||
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 89,017 | 1,150,000 | 0.97% | ||
| 22 | Allianz Asset Management GmbH | 80,050 | 1,035,000 | 0.87% | ||
| 23 | Bank of New York Mellon Corp | 73,549 | 951,000 | 0.80% | ||
| 24 | OXFORD ASSET MANAGEMENT LLP | 54,529 | 699,000 | 0.59% | ||
| 25 | DAFNA Capital Management LLC | 50,000 | 647,000 | 0.55% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 48,276 | 624,000 | 0.53% | ||
| 27 | NORTHERN TRUST CORP | 46,922 | 607,000 | 0.51% | ||
| 28 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 46,000 | 595,000 | 0.50% | ||
| 29 | BlackRock Fund Advisors | 38,279 | 495,000 | 0.42% | ||
| 30 | ELLINGTON MANAGEMENT GROUP LLC | 24,086 | 311,000 | 0.26% | ||
| 31 | D. E. Shaw & Co., Inc. | 15,650 | 202,000 | 0.17% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 14,300 | 185,000 | 0.16% | Call | |
| 33 | MENTA CAPITAL LLC | 13,590 | 176,000 | 0.15% | ||
| 34 | DEUTSCHE BANK AG\ | 13,389 | 173,000 | 0.15% | ||
| 35 | STATE STREET CORP | 13,300 | 172,000 | 0.15% | ||
| 36 | GOLDMAN SACHS GROUP INC | 11,689 | 151,000 | 0.13% | ||
| 37 | CREDIT SUISSE AG/ | 11,502 | 149,000 | 0.13% | ||
| 38 | MORGAN STANLEY | 6,729 | 87,000 | 0.07% | ||
| 39 | WELLS FARGO & COMPANY/MN | 6,026 | 78,000 | 0.07% | ||
| 40 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 4,215 | 54,000 | 0.05% | ||
| 41 | BlackRock Investment Management, LLC | 2,629 | 34,000 | 0.03% | ||
| 42 | CUTLER GROUP LLC / CA | 2,200 | 28,000 | 0.02% | ||
| 43 | UBS Group AG | 2,178 | 28,000 | 0.02% | ||
| 44 | BLACKROCK ADVISORS LLC | 1,692 | 22,000 | 0.02% | ||
| 45 | ADVANTAGE INVESTMENT MANAGEMENT, LLC | 1,450 | 19,000 | 0.02% | ||
| 46 | CITIGROUP INC | 1,382 | 18,000 | 0.02% | ||
| 47 | CUTLER GROUP LLC / CA | 4,200 | 11,000 | 0.01% | Call | |
| 48 | CUTLER GROUP LLC / CA | 17,000 | 11,000 | 0.01% | Put | |
| 49 | SIMPLEX TRADING, LLC | 206 | 2,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
