| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Bank of New York Mellon Corp | 607,666 | 5,299,000 | 11.53% | ||
| 2 | FMR LLC | 575,000 | 5,014,000 | 10.91% | ||
| 3 | BlackRock Fund Advisors | 514,223 | 4,484,000 | 9.76% | ||
| 4 | PERCEPTIVE ADVISORS LLC | 485,338 | 4,232,000 | 9.21% | ||
| 5 | FRANKLIN RESOURCES INC | 475,600 | 4,147,000 | 9.02% | ||
| 6 | Novo Holdings A/S | 470,946 | 4,107,000 | 8.94% | ||
| 7 | AMERIPRISE FINANCIAL INC | 285,082 | 2,485,000 | 5.41% | ||
| 8 | Alyeska Investment Group, L.P. | 251,797 | 2,196,000 | 4.78% | ||
| 9 | VANGUARD GROUP INC | 240,466 | 2,097,000 | 4.56% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 134,010 | 1,169,000 | 2.54% | ||
| 11 | Green Owl Capital Management, LLC | 132,500 | 1,155,000 | 2.51% | ||
| 12 | NORTHERN TRUST CORP | 118,552 | 1,034,000 | 2.25% | ||
| 13 | PUTNAM INVESTMENTS LLC | 100,246 | 874,000 | 1.90% | ||
| 14 | JPMORGAN CHASE & CO | 95,017 | 828,000 | 1.80% | ||
| 15 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 87,983 | 767,000 | 1.67% | ||
| 16 | STATE STREET CORP | 80,913 | 706,000 | 1.54% | ||
| 17 | Opus Point Partners Management, LLC | 62,007 | 541,000 | 1.18% | ||
| 18 | GEODE CAPITAL MANAGEMENT, LLC | 52,619 | 458,000 | 1.00% | ||
| 19 | RENAISSANCE TECHNOLOGIES LLC | 42,200 | 368,000 | 0.80% | ||
| 20 | MILLENNIUM MANAGEMENT LLC | 41,131 | 359,000 | 0.78% | ||
| 21 | DEUTSCHE BANK AG\ | 37,767 | 328,000 | 0.71% | ||
| 22 | NJ State Employees Deferred Compensation Plan | 35,000 | 305,000 | 0.66% | ||
| 23 | BlackRock Investment Management, LLC | 34,804 | 303,000 | 0.66% | ||
| 24 | TIAA CREF INVESTMENT MANAGEMENT LLC | 34,017 | 297,000 | 0.65% | ||
| 25 | ALPS ADVISORS INC | 29,753 | 259,000 | 0.56% | ||
| 26 | A.R.T. Advisors, LLC | 27,490 | 239,000 | 0.52% | ||
| 27 | CREDIT SUISSE AG/ | 20,045 | 175,000 | 0.38% | ||
| 28 | ProShare Advisors LLC | 19,545 | 170,000 | 0.37% | ||
| 29 | D. E. Shaw & Co., Inc. | 18,123 | 158,000 | 0.34% | ||
| 30 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 17,900 | 157,000 | 0.34% | ||
| 31 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 17,580 | 153,000 | 0.33% | ||
| 32 | GOLDMAN SACHS GROUP INC | 16,702 | 146,000 | 0.32% | ||
| 33 | BANK OF AMERICA CORP /DE/ | 14,875 | 129,000 | 0.28% | ||
| 34 | TEACHERS ADVISORS, LLC | 13,864 | 121,000 | 0.26% | ||
| 35 | CITIGROUP INC | 12,697 | 111,000 | 0.24% | ||
| 36 | RHUMBLINE ADVISERS | 10,798 | 94,000 | 0.20% | ||
| 37 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 10,000 | 87,000 | 0.19% | ||
| 38 | NEW YORK STATE COMMON RETIREMENT FUND | 8,600 | 75,000 | 0.16% | ||
| 39 | Nationwide Fund Advisors | 6,088 | 53,000 | 0.12% | ||
| 40 | ROPES WEALTH ADVISORS LLC | 6,000 | 52,000 | 0.11% | ||
| 41 | AMERICAN INTERNATIONAL GROUP, INC. | 5,553 | 48,000 | 0.10% | ||
| 42 | MORGAN STANLEY | 5,094 | 45,000 | 0.10% | ||
| 43 | BLACKROCK ADVISORS LLC | 4,135 | 36,000 | 0.08% | ||
| 44 | Creative Planning | 3,300 | 29,000 | 0.06% | ||
| 45 | COLONY GROUP LLC | 2,000 | 17,000 | 0.04% | ||
| 46 | BNP PARIBAS FINANCIAL MARKETS | 1,279 | 11,153 | 0.02% | ||
| 47 | UBS Group AG | 1,241 | 11,000 | 0.02% | ||
| 48 | Tower Research Capital LLC (TRC) | 1,144 | 10,000 | 0.02% | ||
| 49 | BlackRock Japan Co. Ltd | 986 | 9,000 | 0.02% | ||
| 50 | BARCLAYS PLC | 440 | 4,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
