| 1 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
4,122,873 |
47,619,000 |
21.00% |
|
|
| 2 |
WELLINGTON MANAGEMENT GROUP LLP |
4,116,885 |
47,550,000 |
20.97% |
|
|
| 3 |
VIKING GLOBAL INVESTORS LP |
2,305,611 |
26,630,000 |
11.75% |
|
|
| 4 |
FMR LLC |
1,462,190 |
16,888,000 |
7.45% |
|
|
| 5 |
VANGUARD GROUP INC |
925,015 |
10,684,000 |
4.71% |
|
|
| 6 |
FRANKLIN RESOURCES INC |
750,000 |
8,663,000 |
3.82% |
|
|
| 7 |
RA CAPITAL MANAGEMENT, L.P. |
725,000 |
8,374,000 |
3.69% |
|
|
| 8 |
CITADEL ADVISORS LLC |
542,722 |
6,268,000 |
2.76% |
|
|
| 9 |
BOGLE INVESTMENT MANAGEMENT L P /DE/ |
496,334 |
5,732,000 |
2.53% |
|
|
| 10 |
SCHONFELD STRATEGIC ADVISORS LLC |
421,409 |
4,868,000 |
2.15% |
|
|
| 11 |
MONASHEE INVESTMENT MANAGEMENT LLC |
330,400 |
3,816,000 |
1.68% |
|
PRN |
| 12 |
Candriam S.C.A. |
325,199 |
3,756,000 |
1.66% |
|
|
| 13 |
BlackRock Finance, Inc. |
303,557 |
3,506,000 |
1.55% |
|
|
| 14 |
LORD, ABBETT & CO. LLC |
300,756 |
3,473,000 |
1.53% |
|
|
| 15 |
Atika Capital Management LLC |
252,000 |
2,910,000 |
1.28% |
|
|
| 16 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
175,794 |
2,030,000 |
0.90% |
|
|
| 17 |
GOLDMAN SACHS GROUP INC |
133,981 |
1,547,000 |
0.68% |
|
|
| 18 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
127,600 |
1,474,000 |
0.65% |
|
|
| 19 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
109,498 |
1,265,000 |
0.56% |
|
|
| 20 |
GEODE CAPITAL MANAGEMENT, LLC |
107,169 |
1,236,000 |
0.55% |
|
|
| 21 |
Informed Momentum Co LLC |
105,650 |
1,220,000 |
0.54% |
|
|
| 22 |
VICTORY CAPITAL MANAGEMENT INC |
101,140 |
1,168,000 |
0.52% |
|
|
| 23 |
TUDOR INVESTMENT CORP ET AL |
99,720 |
1,152,000 |
0.51% |
|
|
| 24 |
MORGAN STANLEY |
98,161 |
1,133,000 |
0.50% |
|
|
| 25 |
GRATICULE ASIA MACRO ADVISORS LLC |
97,560 |
1,127,000 |
0.50% |
|
|
| 26 |
INTERNATIONAL BIOTECHNOLOGY TRUST PLC |
93,299 |
1,078,000 |
0.48% |
|
|
| 27 |
MILLENNIUM MANAGEMENT LLC |
75,328 |
870,000 |
0.38% |
|
|
| 28 |
D. E. Shaw & Co., Inc. |
72,121 |
833,000 |
0.37% |
|
|
| 29 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
65,700 |
759,000 |
0.33% |
Put |
|
| 30 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
55,600 |
642,000 |
0.28% |
Call |
|
| 31 |
Laurion Capital Management LP |
43,600 |
504,000 |
0.22% |
|
|
| 32 |
SIMPLEX TRADING, LLC |
43,155 |
498,000 |
0.22% |
|
|
| 33 |
BARCLAYS PLC |
35,398 |
409,000 |
0.18% |
|
|
| 34 |
ACADIAN ASSET MANAGEMENT LLC |
33,010 |
381,000 |
0.17% |
|
|
| 35 |
Bank of New York Mellon Corp |
32,688 |
377,000 |
0.17% |
|
|
| 36 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
29,600 |
342,000 |
0.15% |
|
|
| 37 |
GSA CAPITAL PARTNERS LLP |
28,330 |
327,000 |
0.14% |
|
|
| 38 |
OXFORD ASSET MANAGEMENT LLP |
28,221 |
326,000 |
0.14% |
|
|
| 39 |
Segantii Capital Management Ltd |
28,036 |
324,000 |
0.14% |
|
|
| 40 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
23,325 |
269,000 |
0.12% |
|
|
| 41 |
ICONIQ Capital, LLC |
23,222 |
268,000 |
0.12% |
|
|
| 42 |
NORTHERN TRUST CORP |
23,204 |
268,000 |
0.12% |
|
|
| 43 |
STATE STREET CORP |
22,100 |
255,000 |
0.11% |
|
|
| 44 |
ELLINGTON MANAGEMENT GROUP LLC |
20,900 |
241,000 |
0.11% |
|
|
| 45 |
CITADEL ADVISORS LLC |
20,700 |
239,000 |
0.11% |
Put |
|
| 46 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
20,500 |
237,000 |
0.10% |
|
|
| 47 |
JANE STREET GROUP, LLC |
19,214 |
222,000 |
0.10% |
|
|
| 48 |
TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY |
18,500 |
214,000 |
0.09% |
|
|
| 49 |
SG Americas Securities, LLC |
18,273 |
211,000 |
0.09% |
|
|
| 50 |
CITADEL ADVISORS LLC |
18,300 |
211,000 |
0.09% |
Call |
|
