| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | JANUS HENDERSON INVESTORS US LLC | 601,307 | 5,562,000 | 18.86% | ||
| 2 | FRANKLIN RESOURCES INC | 395,000 | 3,654,000 | 12.39% | ||
| 3 | Point72 Asset Management, L.P. | 340,000 | 3,145,000 | 10.66% | ||
| 4 | MILLENNIUM MANAGEMENT LLC | 254,198 | 2,351,000 | 7.97% | ||
| 5 | Avoro Capital Advisors LLC | 228,697 | 2,115,000 | 7.17% | ||
| 6 | BAKER BROS. ADVISORS LP | 211,792 | 1,959,000 | 6.64% | ||
| 7 | Opaleye Management Inc. | 195,000 | 1,804,000 | 6.12% | ||
| 8 | DEERFIELD MANAGEMENT COMPANY, L.P. | 172,307 | 1,594,000 | 5.40% | ||
| 9 | EverPoint Asset Management, LLC | 150,529 | 1,392,000 | 4.72% | ||
| 10 | OXFORD ASSET MANAGEMENT LLP | 147,819 | 1,367,000 | 4.63% | ||
| 11 | SPHERA FUNDS MANAGEMENT LTD. | 132,300 | 1,224,000 | 4.15% | ||
| 12 | Candriam S.C.A. | 110,000 | 1,016,000 | 3.44% | ||
| 13 | PUTNAM INVESTMENTS LLC | 100,000 | 925,000 | 3.14% | ||
| 14 | PERCEPTIVE ADVISORS LLC | 30,000 | 278,000 | 0.94% | ||
| 15 | RENAISSANCE TECHNOLOGIES LLC | 25,478 | 236,000 | 0.80% | ||
| 16 | Private Capital Advisors, Inc. | 25,000 | 231,000 | 0.78% | ||
| 17 | TFS CAPITAL LLC | 14,300 | 132,000 | 0.45% | ||
| 18 | SABBY MANAGEMENT, LLC | 14,137 | 131,000 | 0.44% | ||
| 19 | Endurant Capital Management LP | 12,500 | 116,000 | 0.39% | ||
| 20 | SCHONFELD STRATEGIC ADVISORS LLC | 10,841 | 100,000 | 0.34% | ||
| 21 | DEUTSCHE BANK AG\ | 6,178 | 57,000 | 0.19% | ||
| 22 | MORGAN STANLEY | 4,889 | 45,000 | 0.15% | ||
| 23 | JPMORGAN CHASE & CO | 3,505 | 32,000 | 0.11% | ||
| 24 | WELLS FARGO & COMPANY/MN | 1,000 | 9,000 | 0.03% | ||
| 25 | Tower Research Capital LLC (TRC) | 1,016 | 9,000 | 0.03% | ||
| 26 | BANK OF AMERICA CORP /DE/ | 800 | 7,000 | 0.02% | ||
| 27 | SEI INVESTMENTS CO | 500 | 5,000 | 0.02% | ||
| 28 | Creative Planning | 100 | 1,000 | 0.00% | ||
| 29 | ROYAL BANK OF CANADA | 143 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
