| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 2,778,654 | 27,509,000 | 12.63% | ||
| 2 | FMR LLC | 2,461,083 | 24,365,000 | 11.18% | ||
| 3 | Sarissa Capital Management LP | 1,132,367 | 11,210,000 | 5.15% | ||
| 4 | STATE STREET CORP | 1,092,615 | 10,818,000 | 4.97% | ||
| 5 | ORACLE INVESTMENT MANAGEMENT INC | 1,014,164 | 10,040,000 | 4.61% | ||
| 6 | PAULSON & CO. INC. | 1,000,000 | 9,900,000 | 4.54% | ||
| 7 | DESTRIER CAPITAL MANAGEMENT LLC | 933,600 | 9,243,000 | 4.24% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 836,154 | 8,278,000 | 3.80% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 826,822 | 8,186,000 | 3.76% | ||
| 10 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 775,307 | 7,675,000 | 3.52% | ||
| 11 | SENZAR ASSET MANAGEMENT, LLC | 753,600 | 7,460,000 | 3.42% | ||
| 12 | FARALLON CAPITAL MANAGEMENT LLC | 700,000 | 6,930,000 | 3.18% | ||
| 13 | VANGUARD GROUP INC | 657,860 | 6,513,000 | 2.99% | ||
| 14 | BlackRock Fund Advisors | 554,898 | 5,493,000 | 2.52% | ||
| 15 | CQS Cayman LP | 550,000 | 5,445,000 | 2.50% | ||
| 16 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 463,100 | 4,585,000 | 2.10% | Call | |
| 17 | GENERAL AMERICAN INVESTORS CO INC | 449,475 | 4,450,000 | 2.04% | ||
| 18 | Visium Asset Management, LP | 391,700 | 3,878,000 | 1.78% | ||
| 19 | MORGAN STANLEY | 330,384 | 3,270,000 | 1.50% | ||
| 20 | BANK OF AMERICA CORP /DE/ | 306,425 | 3,033,000 | 1.39% | ||
| 21 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 297,000 | 2,940,000 | 1.35% | Put | |
| 22 | SABBY MANAGEMENT, LLC | 295,621 | 2,927,000 | 1.34% | ||
| 23 | NORTHERN TRUST CORP | 277,935 | 2,751,000 | 1.26% | ||
| 24 | Gruss Capital Management LP | 250,000 | 2,475,000 | 1.14% | ||
| 25 | BARCLAYS PLC | 208,500 | 1,877,000 | 0.86% | Put | |
| 26 | CREDIT SUISSE AG/ | 170,402 | 1,687,000 | 0.77% | ||
| 27 | BARCLAYS PLC | 171,455 | 1,542,000 | 0.71% | ||
| 28 | Bank of New York Mellon Corp | 126,205 | 1,249,000 | 0.57% | ||
| 29 | PACIFIC ALTERNATIVE ASSET MANAGEMENT COMPANY, LLC | 125,700 | 1,244,000 | 0.57% | Call | |
| 30 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 120,147 | 1,189,000 | 0.55% | ||
| 31 | DESTRIER CAPITAL MANAGEMENT LLC | 120,000 | 1,188,000 | 0.55% | Call | |
| 32 | GEODE CAPITAL MANAGEMENT, LLC | 119,760 | 1,185,000 | 0.54% | ||
| 33 | CITADEL ADVISORS LLC | 114,251 | 1,131,000 | 0.52% | ||
| 34 | BARCLAYS PLC | 114,500 | 1,031,000 | 0.47% | Call | |
| 35 | PDT Partners, LLC | 100,121 | 991,000 | 0.45% | ||
| 36 | TIAA CREF INVESTMENT MANAGEMENT LLC | 98,085 | 971,000 | 0.45% | ||
| 37 | Spot Trading L.L.C | 77,500 | 767,000 | 0.35% | Put | |
| 38 | BlackRock Investment Management, LLC | 68,211 | 675,000 | 0.31% | ||
| 39 | Allianz Asset Management GmbH | 63,919 | 633,000 | 0.29% | ||
| 40 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 62,498 | 619,000 | 0.28% | ||
| 41 | NOMURA HOLDINGS INC | 55,535 | 576,000 | 0.26% | ||
| 42 | BANK OF MONTREAL /CAN/ | 57,200 | 566,000 | 0.26% | Call | |
| 43 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 54,000 | 535,000 | 0.25% | ||
| 44 | Trellus Management Company, LLC | 50,000 | 495,000 | 0.23% | Call | |
| 45 | GOLDMAN SACHS GROUP INC | 48,600 | 481,000 | 0.22% | Call | |
| 46 | GOLDMAN SACHS GROUP INC | 47,264 | 468,000 | 0.21% | ||
| 47 | Spot Trading L.L.C | 44,565 | 441,000 | 0.20% | ||
| 48 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 42,631 | 422,000 | 0.19% | ||
| 49 | TEACHERS ADVISORS, LLC | 37,439 | 371,000 | 0.17% | ||
| 50 | D. E. Shaw & Co., Inc. | 36,811 | 365,000 | 0.17% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
