| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 3,237,000 | 68,301,000 | 10.21% | ||
| 2 | PERCEPTIVE ADVISORS LLC | 2,596,691 | 54,790,000 | 8.19% | ||
| 3 | VANGUARD GROUP INC | 2,207,753 | 46,584,000 | 6.97% | ||
| 4 | BlackRock Fund Advisors | 1,381,334 | 29,146,000 | 4.36% | ||
| 5 | STATE STREET CORP | 1,298,541 | 27,402,000 | 4.10% | ||
| 6 | FMR LLC | 1,257,433 | 26,532,000 | 3.97% | ||
| 7 | PERCEPTIVE ADVISORS LLC | 1,250,000 | 26,375,000 | 3.94% | Call | |
| 8 | BlackRock Institutional Trust Company, N.A. | 1,076,769 | 22,720,000 | 3.40% | ||
| 9 | JENNISON ASSOCIATES LLC | 1,023,834 | 21,603,000 | 3.23% | ||
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 875,600 | 18,475,000 | 2.76% | Call | |
| 11 | GILDER GAGNON HOWE & CO LLC | 840,982 | 17,745,000 | 2.65% | ||
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 779,900 | 16,456,000 | 2.46% | Put | |
| 13 | D. E. Shaw & Co., Inc. | 762,260 | 16,083,000 | 2.41% | ||
| 14 | PointState Capital LP | 725,000 | 15,298,000 | 2.29% | ||
| 15 | LORD, ABBETT & CO. LLC | 695,278 | 14,670,000 | 2.19% | ||
| 16 | Point72 Asset Management, L.P. | 691,200 | 14,584,000 | 2.18% | Call | |
| 17 | KORNITZER CAPITAL MANAGEMENT INC /KS | 648,480 | 13,683,000 | 2.05% | ||
| 18 | Granahan Investment Management, LLC | 630,282 | 13,299,000 | 1.99% | ||
| 19 | COMMERZBANK AKTIENGESELLSCHAFT /FI | 521,068 | 10,995,000 | 1.64% | ||
| 20 | BANK OF AMERICA CORP /DE/ | 486,216 | 10,260,000 | 1.53% | ||
| 21 | NORTHERN TRUST CORP | 458,589 | 9,676,000 | 1.45% | ||
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 416,793 | 8,794,000 | 1.32% | ||
| 23 | BANK OF AMERICA CORP /DE/ | 403,300 | 8,510,000 | 1.27% | Put | |
| 24 | EMERALD ADVISERS, LLC | 400,585 | 8,452,000 | 1.26% | ||
| 25 | Tekla Capital Management LLC | 345,400 | 7,288,000 | 1.09% | Call | |
| 26 | Tekla Capital Management LLC | 345,400 | 7,288,000 | 1.09% | ||
| 27 | GOLDMAN SACHS GROUP INC | 328,200 | 6,925,000 | 1.04% | Call | |
| 28 | Jefferies Group LLC | 325,000 | 6,858,000 | 1.03% | Call | |
| 29 | SOROS FUND MANAGEMENT LLC | 325,000 | 6,858,000 | 1.03% | ||
| 30 | TIAA CREF INVESTMENT MANAGEMENT LLC | 271,815 | 5,735,000 | 0.86% | ||
| 31 | EVENTIDE ASSET MANAGEMENT, LLC | 259,100 | 5,467,000 | 0.82% | ||
| 32 | HIGHLAND CAPITAL MANAGEMENT LP | 253,412 | 5,347,000 | 0.80% | ||
| 33 | Point72 Asset Management, L.P. | 227,300 | 4,796,000 | 0.72% | ||
| 34 | EMERALD MUTUAL FUND ADVISERS TRUST | 217,693 | 4,593,000 | 0.69% | ||
| 35 | GEODE CAPITAL MANAGEMENT, LLC | 215,944 | 4,555,000 | 0.68% | ||
| 36 | Bank of New York Mellon Corp | 215,013 | 4,538,000 | 0.68% | ||
| 37 | CREDIT SUISSE AG/ | 200,000 | 4,220,000 | 0.63% | Call | |
| 38 | Jefferies Group LLC | 183,806 | 3,878,000 | 0.58% | ||
| 39 | Jefferies Group LLC | 138,300 | 2,918,000 | 0.44% | Put | |
| 40 | GUGGENHEIM CAPITAL LLC | 126,177 | 2,662,000 | 0.40% | ||
| 41 | BlackRock Investment Management, LLC | 111,691 | 2,357,000 | 0.35% | ||
| 42 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 109,375 | 2,308,000 | 0.35% | ||
| 43 | CREDIT SUISSE AG/ | 108,907 | 2,299,000 | 0.34% | ||
| 44 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 106,800 | 2,253,000 | 0.34% | ||
| 45 | SABBY MANAGEMENT, LLC | 106,663 | 2,251,000 | 0.34% | ||
| 46 | TEACHERS ADVISORS, LLC | 105,080 | 2,217,000 | 0.33% | ||
| 47 | MORGAN STANLEY | 101,329 | 2,138,000 | 0.32% | ||
| 48 | PALISADE CAPITAL MANAGEMENT, LP | 94,503 | 1,994,000 | 0.30% | ||
| 49 | Spot Trading L.L.C | 94,100 | 1,986,000 | 0.30% | Call | |
| 50 | MILLENNIUM MANAGEMENT LLC | 87,604 | 1,848,000 | 0.28% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
