| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PERCEPTIVE ADVISORS LLC | 2,784,928 | 89,424,000 | 9.06% | ||
| 2 | VANGUARD GROUP INC | 2,571,591 | 82,574,000 | 8.37% | ||
| 3 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 2,133,684 | 68,513,000 | 6.94% | ||
| 4 | FMR LLC | 2,076,212 | 66,667,000 | 6.75% | ||
| 5 | BlackRock Fund Advisors | 1,570,016 | 50,413,000 | 5.11% | ||
| 6 | STATE STREET CORP | 1,345,031 | 43,185,000 | 4.37% | ||
| 7 | D. E. Shaw & Co., Inc. | 1,061,532 | 34,086,000 | 3.45% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 936,149 | 30,060,000 | 3.05% | ||
| 9 | CITADEL ADVISORS LLC | 918,047 | 29,478,000 | 2.99% | ||
| 10 | Point72 Asset Management, L.P. | 910,370 | 29,232,000 | 2.96% | ||
| 11 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 758,200 | 24,346,000 | 2.47% | Put | |
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 649,396 | 20,852,000 | 2.11% | ||
| 13 | BLACKROCK ADVISORS LLC | 645,019 | 20,711,000 | 2.10% | ||
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 625,000 | 20,069,000 | 2.03% | Call | |
| 15 | MILLENNIUM MANAGEMENT LLC | 545,471 | 17,515,000 | 1.77% | ||
| 16 | RENAISSANCE TECHNOLOGIES LLC | 507,738 | 16,303,000 | 1.65% | ||
| 17 | NORTHERN TRUST CORP | 469,114 | 15,063,000 | 1.53% | ||
| 18 | Avoro Capital Advisors LLC | 469,025 | 15,060,000 | 1.53% | ||
| 19 | OXFORD ASSET MANAGEMENT LLP | 421,974 | 13,550,000 | 1.37% | ||
| 20 | PointState Capital LP | 400,000 | 12,844,000 | 1.30% | ||
| 21 | HIGHLAND CAPITAL MANAGEMENT LP | 384,461 | 12,345,000 | 1.25% | ||
| 22 | EMERALD ADVISERS, LLC | 362,891 | 11,652,000 | 1.18% | ||
| 23 | EVENTIDE ASSET MANAGEMENT, LLC | 326,400 | 10,481,000 | 1.06% | ||
| 24 | EMERALD MUTUAL FUND ADVISERS TRUST | 322,970 | 10,371,000 | 1.05% | ||
| 25 | DEUTSCHE BANK AG\ | 312,390 | 10,029,000 | 1.02% | ||
| 26 | Invesco Ltd. | 308,872 | 9,918,000 | 1.00% | ||
| 27 | GROUP ONE TRADING LLC | 304,614 | 9,781,000 | 0.99% | ||
| 28 | PERCEPTIVE ADVISORS LLC | 300,000 | 9,634,000 | 0.98% | Call | |
| 29 | PDT Partners, LLC | 288,429 | 9,261,000 | 0.94% | ||
| 30 | Jefferies Group LLC | 259,100 | 8,320,000 | 0.84% | Call | |
| 31 | GEODE CAPITAL MANAGEMENT, LLC | 250,104 | 8,030,000 | 0.81% | ||
| 32 | Bank of New York Mellon Corp | 204,189 | 6,557,000 | 0.66% | ||
| 33 | TIAA CREF INVESTMENT MANAGEMENT LLC | 197,833 | 6,352,000 | 0.64% | ||
| 34 | Allianz Asset Management GmbH | 186,265 | 5,981,000 | 0.61% | ||
| 35 | BARCLAYS PLC | 181,600 | 5,811,000 | 0.59% | Put | |
| 36 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 177,100 | 5,687,000 | 0.58% | ||
| 37 | BlackRock Investment Management, LLC | 174,606 | 5,607,000 | 0.57% | ||
| 38 | WELLS FARGO & COMPANY/MN | 150,457 | 4,831,000 | 0.49% | ||
| 39 | JENNISON ASSOCIATES LLC | 148,798 | 4,778,000 | 0.48% | ||
| 40 | J. Goldman & Co LP | 140,000 | 4,495,000 | 0.46% | Call | |
| 41 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 129,622 | 4,163,000 | 0.42% | ||
| 42 | KORNITZER CAPITAL MANAGEMENT INC /KS | 129,380 | 4,154,000 | 0.42% | ||
| 43 | GOLDMAN SACHS GROUP INC | 121,500 | 3,901,000 | 0.40% | Call | |
| 44 | BlackRock Group LTD | 117,252 | 3,766,000 | 0.38% | ||
| 45 | TEACHERS ADVISORS, LLC | 109,319 | 3,510,000 | 0.36% | ||
| 46 | MORGAN STANLEY | 109,308 | 3,510,000 | 0.36% | ||
| 47 | CREDIT SUISSE AG/ | 103,964 | 3,339,000 | 0.34% | ||
| 48 | AMERIPRISE FINANCIAL INC | 101,232 | 3,251,000 | 0.33% | ||
| 49 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 100,000 | 3,211,000 | 0.33% | Call | |
| 50 | A.R.T. Advisors, LLC | 91,056 | 2,923,000 | 0.30% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
