| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 3,532,677 | 107,499,000 | 12.02% | ||
| 2 | PERCEPTIVE ADVISORS LLC | 2,809,528 | 85,494,000 | 9.56% | ||
| 3 | VANGUARD GROUP INC | 2,502,173 | 76,142,000 | 8.51% | ||
| 4 | FMR LLC | 2,076,212 | 63,179,000 | 7.06% | ||
| 5 | STATE STREET CORP | 1,579,119 | 48,047,000 | 5.37% | ||
| 6 | BlackRock Fund Advisors | 1,528,833 | 46,522,000 | 5.20% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 1,108,316 | 33,726,000 | 3.77% | ||
| 8 | Point72 Asset Management, L.P. | 936,600 | 28,501,000 | 3.19% | ||
| 9 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 792,600 | 24,119,000 | 2.70% | Call | |
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 633,500 | 19,277,000 | 2.15% | Put | |
| 11 | BLACKROCK ADVISORS LLC | 624,046 | 18,990,000 | 2.12% | ||
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 600,996 | 18,288,000 | 2.04% | ||
| 13 | PointState Capital LP | 575,000 | 17,497,000 | 1.96% | ||
| 14 | D. E. Shaw & Co., Inc. | 516,376 | 15,714,000 | 1.76% | ||
| 15 | Invesco Ltd. | 506,676 | 15,418,000 | 1.72% | ||
| 16 | PERCEPTIVE ADVISORS LLC | 500,000 | 15,215,000 | 1.70% | Call | |
| 17 | NORTHERN TRUST CORP | 458,066 | 13,939,000 | 1.56% | ||
| 18 | HealthCor Management, L.P. | 365,000 | 11,107,000 | 1.24% | ||
| 19 | JENNISON ASSOCIATES LLC | 353,000 | 10,742,000 | 1.20% | ||
| 20 | EMERALD ADVISERS, LLC | 350,127 | 10,654,000 | 1.19% | ||
| 21 | HIGHLAND CAPITAL MANAGEMENT LP | 331,909 | 10,100,000 | 1.13% | ||
| 22 | RENAISSANCE TECHNOLOGIES LLC | 295,178 | 8,982,000 | 1.00% | ||
| 23 | WELLS FARGO & COMPANY/MN | 282,637 | 8,601,000 | 0.96% | ||
| 24 | EMERALD MUTUAL FUND ADVISERS TRUST | 263,520 | 8,019,000 | 0.90% | ||
| 25 | EVENTIDE ASSET MANAGEMENT, LLC | 259,100 | 7,884,000 | 0.88% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 243,573 | 7,411,000 | 0.83% | ||
| 27 | Bank of New York Mellon Corp | 241,477 | 7,348,000 | 0.82% | ||
| 28 | GROUP ONE TRADING LLC | 230,996 | 7,029,000 | 0.79% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 197,608 | 6,013,000 | 0.67% | ||
| 30 | DEUTSCHE BANK AG\ | 194,047 | 5,903,000 | 0.66% | ||
| 31 | LORD, ABBETT & CO. LLC | 191,314 | 5,822,000 | 0.65% | ||
| 32 | Jefferies Group LLC | 191,100 | 5,815,000 | 0.65% | Call | |
| 33 | BlackRock Investment Management, LLC | 178,960 | 5,446,000 | 0.61% | ||
| 34 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 177,100 | 5,389,000 | 0.60% | ||
| 35 | Point72 Asset Management, L.P. | 174,900 | 5,322,000 | 0.59% | Call | |
| 36 | KORNITZER CAPITAL MANAGEMENT INC /KS | 160,045 | 4,870,000 | 0.54% | ||
| 37 | SPHERA FUNDS MANAGEMENT LTD. | 150,000 | 4,565,000 | 0.51% | ||
| 38 | CREDIT SUISSE AG/ | 140,864 | 4,286,000 | 0.48% | ||
| 39 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 125,848 | 3,830,000 | 0.43% | ||
| 40 | UBS Group AG | 124,978 | 3,803,000 | 0.43% | ||
| 41 | MORGAN STANLEY | 121,061 | 3,684,000 | 0.41% | ||
| 42 | CITADEL ADVISORS LLC | 112,842 | 3,434,000 | 0.38% | ||
| 43 | TEACHERS ADVISORS, LLC | 109,143 | 3,321,000 | 0.37% | ||
| 44 | GOLDMAN SACHS GROUP INC | 106,808 | 3,250,000 | 0.36% | ||
| 45 | AMERIPRISE FINANCIAL INC | 106,627 | 3,245,000 | 0.36% | ||
| 46 | OXFORD ASSET MANAGEMENT LLP | 102,692 | 3,125,000 | 0.35% | ||
| 47 | MACQUARIE GROUP LTD | 90,000 | 2,739,000 | 0.31% | ||
| 48 | Benchmark Capital Advisors | 88,350 | 2,688,000 | 0.30% | ||
| 49 | PDT Partners, LLC | 75,819 | 2,307,000 | 0.26% | ||
| 50 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 75,732 | 2,305,000 | 0.26% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
