| 1 |
Essex Woodlands Management, Inc. |
3,813,196 |
83,509,000 |
34.05% |
|
|
| 2 |
SV Health Investors, LLC |
3,489,533 |
76,421,000 |
31.16% |
|
|
| 3 |
FMR LLC |
1,001,776 |
21,939,000 |
8.94% |
|
|
| 4 |
RS INVESTMENT MANAGEMENT CO LLC |
587,930 |
12,876,000 |
5.25% |
|
|
| 5 |
LORD, ABBETT & CO. LLC |
294,298 |
6,445,000 |
2.63% |
|
|
| 6 |
WELLS FARGO & COMPANY/MN |
249,780 |
5,470,000 |
2.23% |
|
|
| 7 |
KINGDON CAPITAL MANAGEMENT, L.L.C. |
245,000 |
5,366,000 |
2.19% |
|
|
| 8 |
PRICE T ROWE ASSOCIATES INC /MD/ |
232,212 |
5,085,000 |
2.07% |
|
|
| 9 |
NEXT CENTURY GROWTH INVESTORS LLC |
150,177 |
3,288,000 |
1.34% |
|
|
| 10 |
Ghost Tree Capital, LLC |
150,000 |
3,285,000 |
1.34% |
|
|
| 11 |
BlackRock Fund Advisors |
145,353 |
3,183,000 |
1.30% |
|
|
| 12 |
AMERICAN CENTURY COMPANIES INC |
120,666 |
2,643,000 |
1.08% |
|
|
| 13 |
WADDELL & REED FINANCIAL INC |
87,700 |
1,921,000 |
0.78% |
|
|
| 14 |
WASATCH ADVISORS LP |
78,000 |
1,708,000 |
0.70% |
|
|
| 15 |
VANGUARD GROUP INC |
65,417 |
1,433,000 |
0.58% |
|
|
| 16 |
FEDERATED HERMES, INC. |
57,757 |
1,265,000 |
0.52% |
|
|
| 17 |
BlackRock Institutional Trust Company, N.A. |
42,302 |
926,000 |
0.38% |
|
|
| 18 |
FRIESS ASSOCIATES LLC |
41,073 |
899,000 |
0.37% |
|
|
| 19 |
WALL STREET ASSOCIATES |
40,000 |
876,000 |
0.36% |
|
|
| 20 |
MILLENNIUM MANAGEMENT LLC |
35,324 |
774,000 |
0.32% |
|
|
| 21 |
D. E. Shaw & Co., Inc. |
35,122 |
769,000 |
0.31% |
|
|
| 22 |
BELLEVUE ASSET MANAGEMENT AG |
30,000 |
657,000 |
0.27% |
|
|
| 23 |
AMERIPRISE FINANCIAL INC |
25,800 |
565,000 |
0.23% |
|
|
| 24 |
MORGAN STANLEY |
19,464 |
427,000 |
0.17% |
|
|
| 25 |
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC |
19,442 |
426,000 |
0.17% |
|
|
| 26 |
Quantitative Systematic Strategies LLC |
18,063 |
415,000 |
0.17% |
|
|
| 27 |
BlackRock Investment Management, LLC |
16,308 |
357,000 |
0.15% |
|
|
| 28 |
NORTHERN TRUST CORP |
14,871 |
325,000 |
0.13% |
|
|
| 29 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13,074 |
286,000 |
0.12% |
|
|
| 30 |
DekaBank Deutsche Girozentrale |
13,000 |
285,000 |
0.12% |
|
|
| 31 |
Laurion Capital Management LP |
12,700 |
278,000 |
0.11% |
|
|
| 32 |
Bank of New York Mellon Corp |
12,609 |
276,000 |
0.11% |
|
|
| 33 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
9,700 |
212,000 |
0.09% |
|
|
| 34 |
JANE STREET GROUP, LLC |
9,667 |
212,000 |
0.09% |
|
|
| 35 |
TEACHERS ADVISORS, LLC |
5,023 |
110,000 |
0.04% |
|
|
| 36 |
AMERICAN INTERNATIONAL GROUP, INC. |
4,000 |
87,600 |
0.04% |
|
|
| 37 |
Tower Research Capital LLC (TRC) |
2,859 |
63,000 |
0.03% |
|
|
| 38 |
BLACKROCK ADVISORS LLC |
2,420 |
53,000 |
0.02% |
|
|
| 39 |
STRS OHIO |
1,800 |
39,000 |
0.02% |
|
|
| 40 |
CITIGROUP INC |
1,565 |
35,000 |
0.01% |
|
|
| 41 |
Nationwide Fund Advisors |
1,345 |
29,000 |
0.01% |
|
|
| 42 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
1,140 |
25,000 |
0.01% |
|
|
| 43 |
UBS Group AG |
500 |
11,000 |
0.00% |
|
|
| 44 |
MAGEE THOMSON INVESTMENT PARTNERS LLC |
246 |
5,000 |
0.00% |
|
|
| 45 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
230 |
5,000 |
0.00% |
|
|
| 46 |
Creative Planning |
200 |
4,000 |
0.00% |
|
|
| 47 |
BNP PARIBAS FINANCIAL MARKETS |
125 |
2,738 |
0.00% |
|
|
| 48 |
BANK OF AMERICA CORP /DE/ |
80 |
2,000 |
0.00% |
|
|
| 49 |
ROYAL BANK OF CANADA |
100 |
2,000 |
0.00% |
|
|
| 50 |
BARCLAYS PLC |
69 |
1,000 |
0.00% |
|
|
