| 1 |
Essex Woodlands Management, Inc. |
3,813,197 |
64,291,000 |
32.35% |
|
|
| 2 |
SV Health Investors, LLC |
3,489,533 |
58,834,000 |
29.60% |
|
|
| 3 |
FMR LLC |
898,400 |
15,147,000 |
7.62% |
|
|
| 4 |
RS INVESTMENT MANAGEMENT CO LLC |
467,157 |
7,876,000 |
3.96% |
|
|
| 5 |
WELLS FARGO & COMPANY/MN |
464,550 |
7,832,000 |
3.94% |
|
|
| 6 |
First Light Asset Management, LLC |
391,497 |
6,601,000 |
3.32% |
|
|
| 7 |
KINGDON CAPITAL MANAGEMENT, L.L.C. |
299,268 |
5,046,000 |
2.54% |
|
|
| 8 |
PRICE T ROWE ASSOCIATES INC /MD/ |
266,642 |
4,496,000 |
2.26% |
|
|
| 9 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
266,630 |
4,495,000 |
2.26% |
|
|
| 10 |
VANGUARD GROUP INC |
185,626 |
3,130,000 |
1.57% |
|
|
| 11 |
Ghost Tree Capital, LLC |
150,000 |
2,529,000 |
1.27% |
|
|
| 12 |
BlackRock Fund Advisors |
147,292 |
2,483,000 |
1.25% |
|
|
| 13 |
WASATCH ADVISORS LP |
141,512 |
2,386,000 |
1.20% |
|
|
| 14 |
AMERIPRISE FINANCIAL INC |
140,925 |
2,376,000 |
1.20% |
|
|
| 15 |
FEDERATED HERMES, INC. |
103,100 |
1,738,000 |
0.87% |
|
|
| 16 |
BlackRock Institutional Trust Company, N.A. |
94,784 |
1,598,000 |
0.80% |
|
|
| 17 |
NORTHERN TRUST CORP |
58,916 |
993,000 |
0.50% |
|
|
| 18 |
Murphy Michael R |
52,971 |
893,000 |
0.45% |
|
|
| 19 |
PUTNAM INVESTMENTS LLC |
47,161 |
795,000 |
0.40% |
|
|
| 20 |
STATE STREET CORP |
47,059 |
791,000 |
0.40% |
|
|
| 21 |
GEODE CAPITAL MANAGEMENT, LLC |
38,488 |
648,000 |
0.33% |
|
|
| 22 |
FRIESS ASSOCIATES LLC |
34,500 |
582,000 |
0.29% |
|
|
| 23 |
Bank of New York Mellon Corp |
25,347 |
427,000 |
0.21% |
|
|
| 24 |
BlackRock Investment Management, LLC |
19,902 |
336,000 |
0.17% |
|
|
| 25 |
KEYBANK NATIONAL ASSOCIATION/OH |
19,481 |
328,000 |
0.17% |
|
|
| 26 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
18,669 |
315,000 |
0.16% |
|
|
| 27 |
D. E. Shaw & Co., Inc. |
17,171 |
290,000 |
0.15% |
|
|
| 28 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
16,560 |
280,000 |
0.14% |
|
|
| 29 |
GSA CAPITAL PARTNERS LLP |
15,882 |
268,000 |
0.13% |
|
|
| 30 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
9,970 |
168,000 |
0.08% |
|
|
| 31 |
TEACHERS ADVISORS, LLC |
8,657 |
146,000 |
0.07% |
|
|
| 32 |
Swiss National Bank |
6,900 |
116,000 |
0.06% |
|
|
| 33 |
Grandeur Peak Global Advisors, LLC |
5,375 |
91,000 |
0.05% |
|
|
| 34 |
NEW YORK STATE COMMON RETIREMENT FUND |
4,900 |
83,000 |
0.04% |
|
|
| 35 |
Nationwide Fund Advisors |
3,538 |
60,000 |
0.03% |
|
|
| 36 |
AMERICAN INTERNATIONAL GROUP, INC. |
3,163 |
53,000 |
0.03% |
|
|
| 37 |
BANK OF AMERICA CORP /DE/ |
3,003 |
51,000 |
0.03% |
|
|
| 38 |
MORGAN STANLEY |
1,973 |
33,000 |
0.02% |
|
|
| 39 |
BLACKROCK ADVISORS LLC |
1,558 |
26,000 |
0.01% |
|
|
| 40 |
DEUTSCHE BANK AG\ |
1,361 |
22,000 |
0.01% |
|
|
| 41 |
UBS Group AG |
1,100 |
19,000 |
0.01% |
|
|
| 42 |
ROYAL BANK OF CANADA |
950 |
16,000 |
0.01% |
|
|
| 43 |
BlackRock Group LTD |
737 |
12,000 |
0.01% |
|
|
| 44 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
617 |
10,000 |
0.01% |
|
|
| 45 |
TEACHER RETIREMENT SYSTEM OF TEXAS |
602 |
10,000 |
0.01% |
|
|
| 46 |
BNP PARIBAS FINANCIAL MARKETS |
516 |
8,700 |
0.00% |
|
|
| 47 |
IFP ADVISORS, INC |
500 |
8,000 |
0.00% |
|
|
| 48 |
MAGEE THOMSON INVESTMENT PARTNERS LLC |
289 |
5,000 |
0.00% |
|
|
| 49 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
230 |
4,000 |
0.00% |
|
|
| 50 |
Tower Research Capital LLC (TRC) |
218 |
4,000 |
0.00% |
|
|
