| 1 |
GENOVESE BURFORD & BROTHERS WEALTH & RETIREMENT PLAN MANAGEMENT, LLC |
62 |
1,000 |
0.00% |
|
|
| 2 |
D'Orazio & Associates, Inc. |
62 |
1,000 |
0.00% |
|
|
| 3 |
TORONTO DOMINION BANK |
135 |
2,000 |
0.00% |
|
|
| 4 |
DEUTSCHE BANK AG\ |
200 |
3,000 |
0.00% |
|
|
| 5 |
NEXT Financial Group, Inc |
250 |
4,000 |
0.00% |
|
|
| 6 |
Creative Planning |
262 |
4,000 |
0.00% |
|
|
| 7 |
WELLS FARGO & COMPANY/MN |
500 |
8,000 |
0.01% |
|
|
| 8 |
UBS Group AG |
700 |
12,000 |
0.01% |
|
|
| 9 |
Tower Research Capital LLC (TRC) |
864 |
14,000 |
0.01% |
|
|
| 10 |
TCI Wealth Advisors, Inc. |
828 |
14,000 |
0.01% |
|
|
| 11 |
MORGAN STANLEY |
1,700 |
28,000 |
0.02% |
|
|
| 12 |
BANK OF AMERICA CORP /DE/ |
2,150 |
36,000 |
0.03% |
|
|
| 13 |
BANK OF MONTREAL /CAN/ |
4,891 |
82,000 |
0.07% |
|
|
| 14 |
SABBY MANAGEMENT, LLC |
18,194 |
305,000 |
0.26% |
|
|
| 15 |
GILDER GAGNON HOWE & CO LLC |
43,541 |
729,000 |
0.63% |
|
|
| 16 |
MILLENNIUM MANAGEMENT LLC |
46,149 |
773,000 |
0.66% |
|
|
| 17 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
48,840 |
818,000 |
0.70% |
|
|
| 18 |
J. Goldman & Co LP |
58,500 |
980,000 |
0.84% |
|
|
| 19 |
ACUTA CAPITAL PARTNERS, LLC |
115,400 |
1,933,000 |
1.66% |
|
|
| 20 |
DRIEHAUS CAPITAL MANAGEMENT LLC |
120,588 |
2,020,000 |
1.74% |
|
|
| 21 |
Opaleye Management Inc. |
125,000 |
2,094,000 |
1.80% |
|
|
| 22 |
SPHERA FUNDS MANAGEMENT LTD. |
134,037 |
2,245,000 |
1.93% |
|
|
| 23 |
First Light Asset Management, LLC |
188,577 |
3,159,000 |
2.71% |
|
|
| 24 |
PURA VIDA INVESTMENTS, LLC |
200,845 |
3,364,000 |
2.89% |
|
|
| 25 |
DAFNA Capital Management LLC |
222,359 |
3,718,000 |
3.19% |
|
|
| 26 |
NEXTHERA CAPITAL LP |
244,310 |
4,092,000 |
3.51% |
|
|
| 27 |
Tekla Capital Management LLC |
460,207 |
7,708,000 |
6.62% |
|
|
| 28 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
650,000 |
10,888,000 |
9.35% |
|
|
| 29 |
Visium Asset Management, LP |
750,000 |
12,563,000 |
10.79% |
|
|
| 30 |
Aisling Capital LLC |
1,021,381 |
17,108,000 |
14.70% |
|
|
| 31 |
ORBIMED ADVISORS LLC |
1,140,325 |
17,470,000 |
15.01% |
|
|
| 32 |
FRANKLIN RESOURCES INC |
1,447,265 |
24,242,000 |
20.82% |
|
|
