| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FRANKLIN RESOURCES INC | 1,402,706 | 22,710,000 | 23.44% | ||
| 2 | Aisling Capital LLC | 975,191 | 15,769,000 | 16.28% | ||
| 3 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 650,000 | 10,511,000 | 10.85% | ||
| 4 | Broadfin Capital, LLC | 586,117 | 9,052,000 | 9.34% | ||
| 5 | ORBIMED ADVISORS LLC | 487,000 | 7,875,000 | 8.13% | ||
| 6 | ACUTA CAPITAL PARTNERS, LLC | 313,524 | 5,070,000 | 5.23% | ||
| 7 | First Light Asset Management, LLC | 302,194 | 4,886,000 | 5.04% | ||
| 8 | MILLENNIUM MANAGEMENT LLC | 274,202 | 4,434,000 | 4.58% | ||
| 9 | PURA VIDA INVESTMENTS, LLC | 194,461 | 3,102,000 | 3.20% | ||
| 10 | SPHERA FUNDS MANAGEMENT LTD. | 188,930 | 3,059,000 | 3.16% | ||
| 11 | Ghost Tree Capital, LLC | 175,000 | 2,830,000 | 2.92% | ||
| 12 | J. Goldman & Co LP | 135,000 | 2,183,000 | 2.25% | ||
| 13 | CQS Cayman LP | 87,400 | 1,413,000 | 1.46% | ||
| 14 | SABBY MANAGEMENT, LLC | 52,169 | 845,000 | 0.87% | ||
| 15 | Tekla Capital Management LLC | 49,322 | 799,000 | 0.82% | ||
| 16 | GILDER GAGNON HOWE & CO LLC | 48,802 | 789,000 | 0.81% | ||
| 17 | DAFNA Capital Management LLC | 44,824 | 707,000 | 0.73% | ||
| 18 | Opaleye Management Inc. | 29,000 | 469,000 | 0.48% | ||
| 19 | GOLDMAN SACHS GROUP INC | 12,929 | 209,000 | 0.22% | ||
| 20 | BANK OF MONTREAL /CAN/ | 4,891 | 79,000 | 0.08% | ||
| 21 | BANK OF AMERICA CORP /DE/ | 1,545 | 25,000 | 0.03% | ||
| 22 | UBS Group AG | 1,147 | 19,000 | 0.02% | ||
| 23 | MORGAN STANLEY | 863 | 14,000 | 0.01% | ||
| 24 | TCI Wealth Advisors, Inc. | 700 | 11,000 | 0.01% | ||
| 25 | WELLS FARGO & COMPANY/MN | 500 | 8,000 | 0.01% | ||
| 26 | Tower Research Capital LLC (TRC) | 513 | 8,000 | 0.01% | ||
| 27 | Creative Planning | 262 | 4,000 | 0.00% | ||
| 28 | CITIGROUP INC | 7 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
