| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Novo Holdings A/S | 3,056,563 | 27,203,000 | 55.33% | ||
| 2 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,273,590 | 11,335,000 | 23.05% | ||
| 3 | Pentwater Capital Management LP | 560,541 | 4,989,000 | 10.15% | ||
| 4 | SPHERA FUNDS MANAGEMENT LTD. | 317,250 | 2,824,000 | 5.74% | ||
| 5 | OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 106,750 | 950,000 | 1.93% | ||
| 6 | MILLENNIUM MANAGEMENT LLC | 48,370 | 430,000 | 0.87% | ||
| 7 | PIPER SANDLER & CO. | 42,460 | 378,000 | 0.77% | ||
| 8 | TD ASSET MANAGEMENT INC | 30,400 | 271,000 | 0.55% | ||
| 9 | VANGUARD GROUP INC | 29,314 | 261,000 | 0.53% | ||
| 10 | PANAGORA ASSET MANAGEMENT INC | 23,339 | 208,000 | 0.42% | ||
| 11 | MPM ASSET MANAGEMENT LLC | 21,806 | 194,000 | 0.39% | ||
| 12 | MORGAN STANLEY | 6,412 | 57,000 | 0.12% | ||
| 13 | Artal Group S.A. | 5,575 | 50,000 | 0.10% | ||
| 14 | UBS Group AG | 1,279 | 11,000 | 0.02% | ||
| 15 | BlackRock Investment Management, LLC | 566 | 5,000 | 0.01% | ||
| 16 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 145 | 1,000 | 0.00% | ||
| 17 | CITIGROUP INC | 106 | 1,000 | 0.00% | ||
| 18 | Genesis Wealth Advisors, LLC | 54 | 480 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
