| 1 |
Novo Holdings A/S |
3,056,563 |
25,583,000 |
57.51% |
|
|
| 2 |
PRICE T ROWE ASSOCIATES INC /MD/ |
1,347,895 |
11,282,000 |
25.36% |
|
|
| 3 |
SPHERA FUNDS MANAGEMENT LTD. |
285,525 |
2,390,000 |
5.37% |
|
|
| 4 |
EverPoint Asset Management, LLC |
218,049 |
1,825,000 |
4.10% |
|
|
| 5 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
105,194 |
880,000 |
1.98% |
|
|
| 6 |
VANGUARD GROUP INC |
59,345 |
496,000 |
1.11% |
|
|
| 7 |
SG Americas Securities, LLC |
52,265 |
437,000 |
0.98% |
|
|
| 8 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
50,000 |
419,000 |
0.94% |
|
|
| 9 |
TD ASSET MANAGEMENT INC |
34,200 |
286,000 |
0.64% |
|
|
| 10 |
Pentwater Capital Management LP |
26,234 |
220,000 |
0.49% |
|
|
| 11 |
GEODE CAPITAL MANAGEMENT, LLC |
25,889 |
216,000 |
0.49% |
|
|
| 12 |
MPM ASSET MANAGEMENT LLC |
21,806 |
183,000 |
0.41% |
|
|
| 13 |
MILLENNIUM MANAGEMENT LLC |
10,023 |
84,000 |
0.19% |
|
|
| 14 |
BlackRock Fund Advisors |
9,157 |
77,000 |
0.17% |
|
|
| 15 |
Artal Group S.A. |
5,575 |
47,000 |
0.11% |
|
|
| 16 |
ACADIAN ASSET MANAGEMENT LLC |
2,631 |
22,000 |
0.05% |
|
|
| 17 |
MORGAN STANLEY |
2,300 |
19,000 |
0.04% |
|
|
| 18 |
Tower Research Capital LLC (TRC) |
800 |
7,000 |
0.02% |
|
|
| 19 |
AMERICAN INTERNATIONAL GROUP, INC. |
750 |
6,000 |
0.01% |
|
|
| 20 |
BlackRock Investment Management, LLC |
566 |
5,000 |
0.01% |
|
|
| 21 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
145 |
1,000 |
0.00% |
|
|
