| 1 |
Novo Holdings A/S |
3,056,563 |
18,951,000 |
56.49% |
|
|
| 2 |
PRICE T ROWE ASSOCIATES INC /MD/ |
1,328,115 |
8,234,000 |
24.54% |
|
|
| 3 |
EverPoint Asset Management, LLC |
356,742 |
2,212,000 |
6.59% |
|
|
| 4 |
SPHERA FUNDS MANAGEMENT LTD. |
278,337 |
1,726,000 |
5.14% |
|
|
| 5 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
90,194 |
559,000 |
1.67% |
|
|
| 6 |
VANGUARD GROUP INC |
75,342 |
467,000 |
1.39% |
|
|
| 7 |
SG Americas Securities, LLC |
56,769 |
352,000 |
1.05% |
|
|
| 8 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
50,000 |
310,000 |
0.92% |
|
|
| 9 |
TD ASSET MANAGEMENT INC |
31,400 |
195,000 |
0.58% |
|
|
| 10 |
GEODE CAPITAL MANAGEMENT, LLC |
25,889 |
160,000 |
0.48% |
|
|
| 11 |
MPM ASSET MANAGEMENT LLC |
21,806 |
135,000 |
0.40% |
|
|
| 12 |
MILLENNIUM MANAGEMENT LLC |
10,042 |
62,000 |
0.18% |
|
|
| 13 |
MORGAN STANLEY |
9,800 |
61,000 |
0.18% |
|
|
| 14 |
BlackRock Fund Advisors |
8,623 |
53,000 |
0.16% |
|
|
| 15 |
Artal Group S.A. |
5,575 |
35,000 |
0.10% |
|
|
| 16 |
ACADIAN ASSET MANAGEMENT LLC |
1,757 |
11,000 |
0.03% |
|
|
| 17 |
Tower Research Capital LLC (TRC) |
1,339 |
8,000 |
0.02% |
|
|
| 18 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
792 |
5,000 |
0.01% |
|
|
| 19 |
AMERICAN INTERNATIONAL GROUP, INC. |
750 |
5,000 |
0.01% |
|
|
| 20 |
BlackRock Investment Management, LLC |
566 |
4,000 |
0.01% |
|
|
| 21 |
BANK OF AMERICA CORP /DE/ |
490 |
3,000 |
0.01% |
|
|
| 22 |
CITIGROUP INC |
14 |
0 |
0.00% |
|
|
