| 1 |
Novo Holdings A/S |
3,056,563 |
24,972,000 |
53.99% |
|
|
| 2 |
PRICE T ROWE ASSOCIATES INC /MD/ |
1,327,315 |
10,844,000 |
23.44% |
|
|
| 3 |
SPHERA FUNDS MANAGEMENT LTD. |
500,137 |
4,086,000 |
8.83% |
|
|
| 4 |
EverPoint Asset Management, LLC |
328,979 |
2,688,000 |
5.81% |
|
|
| 5 |
VANGUARD GROUP INC |
76,242 |
623,000 |
1.35% |
|
|
| 6 |
FMR LLC |
67,777 |
554,000 |
1.20% |
|
|
| 7 |
SOCIETE GENERALE |
56,769 |
464,000 |
1.00% |
|
|
| 8 |
SG Americas Securities, LLC |
56,769 |
464,000 |
1.00% |
|
|
| 9 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
50,000 |
409,000 |
0.88% |
|
|
| 10 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
44,994 |
368,000 |
0.80% |
|
|
| 11 |
TD ASSET MANAGEMENT INC |
30,900 |
252,000 |
0.54% |
|
|
| 12 |
GEODE CAPITAL MANAGEMENT, LLC |
25,889 |
211,000 |
0.46% |
|
|
| 13 |
MPM ASSET MANAGEMENT LLC |
21,806 |
178,000 |
0.38% |
|
|
| 14 |
BlackRock Fund Advisors |
8,497 |
69,000 |
0.15% |
|
|
| 15 |
Artal Group S.A. |
5,575 |
46,000 |
0.10% |
|
|
| 16 |
ACADIAN ASSET MANAGEMENT LLC |
840 |
7,000 |
0.02% |
|
|
| 17 |
ADVISOR GROUP, INC. |
750 |
6,000 |
0.01% |
|
|
| 18 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
647 |
5,000 |
0.01% |
|
|
| 19 |
BlackRock Investment Management, LLC |
566 |
5,000 |
0.01% |
|
|
| 20 |
MORGAN STANLEY |
500 |
4,000 |
0.01% |
|
|
