| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PRIMECAP MANAGEMENT CO/CA/ | 3,850,000 | 13,398,000 | 21.71% | ||
| 2 | Alpha Wave Global, LP | 2,618,000 | 9,111,000 | 14.76% | ||
| 3 | HealthCor Management, L.P. | 2,258,300 | 7,859,000 | 12.74% | ||
| 4 | D. E. Shaw & Co., Inc. | 1,741,895 | 6,062,000 | 9.82% | ||
| 5 | SABBY MANAGEMENT, LLC | 1,176,031 | 4,093,000 | 6.63% | ||
| 6 | BANK OF MONTREAL /CAN/ | 810,785 | 2,822,000 | 4.57% | ||
| 7 | AXA S.A. | 792,358 | 2,757,000 | 4.47% | ||
| 8 | GOLDMAN SACHS GROUP INC | 680,546 | 2,368,000 | 3.84% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 586,076 | 2,040,000 | 3.31% | ||
| 10 | SUFFOLK CAPITAL MANAGEMENT LLC | 441,915 | 1,538,000 | 2.49% | ||
| 11 | ARMISTICE CAPITAL, LLC | 408,000 | 1,420,000 | 2.30% | ||
| 12 | SPHERA FUNDS MANAGEMENT LTD. | 300,000 | 1,044,000 | 1.69% | ||
| 13 | I.G. INVESTMENT MANAGEMENT, LTD. | 250,000 | 870,000 | 1.41% | ||
| 14 | BAILARD, INC. | 215,000 | 748,000 | 1.21% | ||
| 15 | DEUTSCHE BANK AG\ | 186,993 | 650,000 | 1.05% | ||
| 16 | BAKER BROS. ADVISORS LP | 180,582 | 628,000 | 1.02% | ||
| 17 | CREDIT SUISSE AG/ | 176,270 | 613,000 | 0.99% | ||
| 18 | MORGAN STANLEY | 99,853 | 347,000 | 0.56% | ||
| 19 | MARINER INVESTMENT GROUP LLC | 89,800 | 313,000 | 0.51% | ||
| 20 | CITIGROUP INC | 78,500 | 273,000 | 0.44% | Put | |
| 21 | RENAISSANCE TECHNOLOGIES LLC | 78,215 | 272,000 | 0.44% | ||
| 22 | DAFNA Capital Management LLC | 75,000 | 261,000 | 0.42% | ||
| 23 | AMERIPRISE FINANCIAL INC | 66,677 | 232,000 | 0.38% | ||
| 24 | VANGUARD GROUP INC | 66,076 | 230,000 | 0.37% | ||
| 25 | K2 PRINCIPAL FUND, L.P. | 63,550 | 221,000 | 0.36% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 47,500 | 165,000 | 0.27% | Put | |
| 27 | MACKENZIE FINANCIAL CORP | 39,900 | 139,000 | 0.23% | ||
| 28 | CITIGROUP INC | 36,860 | 128,000 | 0.21% | ||
| 29 | TFS CAPITAL LLC | 30,860 | 107,000 | 0.17% | ||
| 30 | PDT Partners, LLC | 30,200 | 105,000 | 0.17% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 29,300 | 102,000 | 0.17% | Call | |
| 32 | GEODE CAPITAL MANAGEMENT, LLC | 25,920 | 90,000 | 0.15% | ||
| 33 | Stanley-Laman Group, Ltd. | 25,722 | 90,000 | 0.15% | ||
| 34 | CITIGROUP INC | 24,900 | 87,000 | 0.14% | Call | |
| 35 | DIALECTIC CAPITAL MANAGEMENT, LP | 25,000 | 87,000 | 0.14% | ||
| 36 | FMR LLC | 19,200 | 67,000 | 0.11% | ||
| 37 | ROYAL BANK OF CANADA | 13,190 | 46,000 | 0.07% | ||
| 38 | GROUP ONE TRADING LLC | 12,374 | 43,000 | 0.07% | ||
| 39 | STATE STREET CORP | 12,469 | 43,000 | 0.07% | ||
| 40 | WEDBUSH SECURITIES INC | 12,000 | 42,000 | 0.07% | ||
| 41 | Jefferies Group LLC | 11,200 | 39,000 | 0.06% | ||
| 42 | CUTLER GROUP LLC / CA | 10,780 | 37,000 | 0.06% | ||
| 43 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 10,624 | 37,000 | 0.06% | ||
| 44 | SIMPLEX TRADING, LLC | 7,110 | 24,000 | 0.04% | ||
| 45 | UBS Group AG | 6,078 | 21,000 | 0.03% | ||
| 46 | WELLS FARGO & COMPANY/MN | 2,995 | 10,000 | 0.02% | ||
| 47 | Tower Research Capital LLC (TRC) | 2,282 | 8,000 | 0.01% | ||
| 48 | JPMORGAN CHASE & CO | 1,400 | 6,000 | 0.01% | ||
| 49 | BANK OF AMERICA CORP /DE/ | 1,850 | 6,000 | 0.01% | ||
| 50 | CUTLER GROUP LLC / CA | 5,900 | 4,000 | 0.01% | Put |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
