| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 114,987,547 | 2,151,417,000 | 68.90% | ||
| 2 | GOLDMAN SACHS GROUP INC | 3,980,990 | 74,484,000 | 2.39% | ||
| 3 | CITADEL ADVISORS LLC | 3,261,838 | 61,029,000 | 1.95% | ||
| 4 | WADDELL & REED FINANCIAL INC | 3,156,830 | 59,064,000 | 1.89% | ||
| 5 | LORD, ABBETT & CO. LLC | 3,007,050 | 56,262,000 | 1.80% | ||
| 6 | PRICE T ROWE ASSOCIATES INC /MD/ | 2,790,538 | 52,211,000 | 1.67% | ||
| 7 | FMR LLC | 2,714,062 | 50,780,000 | 1.63% | ||
| 8 | Hitchwood Capital Management LP | 2,450,000 | 45,840,000 | 1.47% | ||
| 9 | VANGUARD GROUP INC | 2,434,087 | 45,542,000 | 1.46% | ||
| 10 | Capital Research Global Investors | 2,248,110 | 42,062,000 | 1.35% | ||
| 11 | ALLIANCEBERNSTEIN L.P. | 2,066,179 | 37,005,000 | 1.19% | ||
| 12 | Clearbridge Investments, LLC | 1,781,358 | 33,329,000 | 1.07% | ||
| 13 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 1,730,750 | 32,382,000 | 1.04% | ||
| 14 | TIAA CREF INVESTMENT MANAGEMENT LLC | 1,572,447 | 29,420,000 | 0.94% | ||
| 15 | Neuberger Berman Group LLC | 1,392,199 | 26,048,000 | 0.83% | ||
| 16 | TimesSquare Capital Management, LLC | 1,236,000 | 23,126,000 | 0.74% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 1,016,445 | 19,018,000 | 0.61% | ||
| 18 | PRIMECAP MANAGEMENT CO/CA/ | 946,566 | 17,710,000 | 0.57% | ||
| 19 | EATON VANCE MANAGEMENT | 820,198 | 15,346,000 | 0.49% | ||
| 20 | FEDERATED HERMES, INC. | 816,000 | 15,267,000 | 0.49% | ||
| 21 | VOYA INVESTMENT MANAGEMENT LLC | 796,292 | 14,899,000 | 0.48% | ||
| 22 | Gotham Asset Management, LLC | 735,810 | 13,767,000 | 0.44% | ||
| 23 | COLUMBUS CIRCLE INVESTORS | 735,708 | 13,765,000 | 0.44% | ||
| 24 | CARBONADO CAPITAL | 700,000 | 13,097,000 | 0.42% | ||
| 25 | PUTNAM INVESTMENTS LLC | 610,064 | 11,414,000 | 0.37% | ||
| 26 | Invesco Ltd. | 563,428 | 10,542,000 | 0.34% | ||
| 27 | STATE STREET CORP | 422,964 | 7,912,000 | 0.25% | ||
| 28 | Allianz Asset Management GmbH | 400,055 | 7,485,000 | 0.24% | ||
| 29 | AMERIPRISE FINANCIAL INC | 394,214 | 7,375,000 | 0.24% | ||
| 30 | Alyeska Investment Group, L.P. | 375,000 | 7,016,000 | 0.22% | ||
| 31 | BALYASNY ASSET MANAGEMENT L.P. | 354,584 | 6,634,000 | 0.21% | ||
| 32 | BlackRock Fund Advisors | 346,076 | 6,475,000 | 0.21% | ||
| 33 | Pier Capital, LLC | 331,988 | 6,211,000 | 0.20% | ||
| 34 | BANK OF AMERICA CORP /DE/ | 319,343 | 5,974,000 | 0.19% | ||
| 35 | GEODE CAPITAL MANAGEMENT, LLC | 310,651 | 5,812,000 | 0.19% | ||
| 36 | HALSEY ASSOCIATES INC/CT | 294,640 | 5,513,000 | 0.18% | ||
| 37 | DEUTSCHE BANK AG\ | 275,366 | 5,150,000 | 0.16% | ||
| 38 | CREDIT SUISSE AG/ | 266,134 | 4,980,000 | 0.16% | ||
| 39 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 263,326 | 4,926,000 | 0.16% | ||
| 40 | MORGAN STANLEY | 208,697 | 3,904,000 | 0.13% | ||
| 41 | THRIVENT FINANCIAL FOR LUTHERANS | 208,500 | 3,901,000 | 0.12% | ||
| 42 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 200,400 | 3,749,000 | 0.12% | ||
| 43 | Bronson Point Management LLC | 200,000 | 3,742,000 | 0.12% | ||
| 44 | TCW GROUP INC | 197,838 | 3,702,000 | 0.12% | ||
| 45 | STEADFAST CAPITAL MANAGEMENT LP | 191,915 | 3,591,000 | 0.12% | ||
| 46 | FOLGER HILL ASSET MANAGEMENT LP | 176,990 | 3,311,000 | 0.11% | ||
| 47 | RENAISSANCE TECHNOLOGIES LLC | 170,300 | 3,186,000 | 0.10% | ||
| 48 | HBK INVESTMENTS L P | 170,000 | 3,181,000 | 0.10% | ||
| 49 | Jupiter Investment Management Ltd | 166,217 | 3,109,000 | 0.10% | ||
| 50 | SEI INVESTMENTS CO | 150,500 | 2,816,000 | 0.09% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
