| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | MPM ASSET MANAGEMENT LLC | 5,736,296 | 16,578,000 | 40.21% | ||
| 2 | FMR LLC | 3,181,101 | 9,194,000 | 22.30% | ||
| 3 | Abingworth LLP | 2,080,595 | 6,013,000 | 14.59% | ||
| 4 | WELLINGTON MANAGEMENT GROUP LLP | 1,275,535 | 3,686,000 | 8.94% | ||
| 5 | Rock Springs Capital Management LP | 492,500 | 1,423,000 | 3.45% | ||
| 6 | VANGUARD GROUP INC | 426,477 | 1,233,000 | 2.99% | ||
| 7 | BlackRock Fund Advisors | 360,485 | 1,042,000 | 2.53% | ||
| 8 | A.R.T. Advisors, LLC | 152,899 | 441,000 | 1.07% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 104,386 | 302,000 | 0.73% | ||
| 10 | CREDIT SUISSE AG/ | 54,846 | 159,000 | 0.39% | ||
| 11 | FIDUCIARY TRUST INTERNATIONAL LLC | 54,131 | 156,000 | 0.38% | ||
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 47,766 | 138,000 | 0.33% | ||
| 13 | MILLENNIUM MANAGEMENT LLC | 32,519 | 94,000 | 0.23% | ||
| 14 | Paloma Partners Management Co | 27,933 | 81,000 | 0.20% | ||
| 15 | VAN ECK ASSOCIATES CORP | 23,658 | 68,000 | 0.16% | ||
| 16 | DEUTSCHE BANK AG\ | 20,768 | 59,000 | 0.14% | ||
| 17 | GOLDMAN SACHS GROUP INC | 19,511 | 56,000 | 0.14% | ||
| 18 | NORTHERN TRUST CORP | 18,367 | 53,000 | 0.13% | ||
| 19 | ProShare Advisors LLC | 18,094 | 52,000 | 0.13% | ||
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 14,801 | 43,000 | 0.10% | ||
| 21 | Squarepoint Ops LLC | 13,900 | 40,000 | 0.10% | ||
| 22 | Rathbones Group PLC | 13,250 | 38,000 | 0.09% | ||
| 23 | SCHRODER INVESTMENT MANAGEMENT GROUP | 12,000 | 35,000 | 0.08% | ||
| 24 | AMP Capital Investors Ltd | 12,000 | 35,000 | 0.08% | ||
| 25 | Psagot Value Holdings Ltd. | 11,645 | 34,000 | 0.08% | ||
| 26 | Bank of New York Mellon Corp | 11,886 | 34,000 | 0.08% | ||
| 27 | BARCLAYS PLC | 9,961 | 29,000 | 0.07% | ||
| 28 | WEDBUSH SECURITIES INC | 10,000 | 29,000 | 0.07% | ||
| 29 | BANK OF AMERICA CORP /DE/ | 4,606 | 13,000 | 0.03% | ||
| 30 | PENSERRA CAPITAL MANAGEMENT LLC | 4,386 | 13,000 | 0.03% | ||
| 31 | MORGAN STANLEY | 3,831 | 11,000 | 0.03% | ||
| 32 | BlackRock Investment Management, LLC | 3,229 | 9,000 | 0.02% | ||
| 33 | ROYAL BANK OF CANADA | 3,000 | 9,000 | 0.02% | ||
| 34 | CITIGROUP INC | 2,899 | 8,000 | 0.02% | ||
| 35 | UBS Group AG | 2,269 | 7,000 | 0.02% | ||
| 36 | INTEGRATED WEALTH MANAGEMENT | 1,500 | 4,000 | 0.01% | ||
| 37 | ACADIAN ASSET MANAGEMENT LLC | 542 | 2,000 | 0.00% | ||
| 38 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 614 | 2,000 | 0.00% | ||
| 39 | WOLVERINE TRADING LP /BD | 345 | 1,004 | 0.00% | ||
| 40 | BLACKROCK ADVISORS LLC | 321 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
