| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | MPM ASSET MANAGEMENT LLC | 5,736,296 | 16,865,000 | 40.32% | ||
| 2 | FMR LLC | 3,189,314 | 9,376,000 | 22.42% | ||
| 3 | Abingworth LLP | 2,080,595 | 6,096,000 | 14.58% | ||
| 4 | WELLINGTON MANAGEMENT GROUP LLP | 1,259,146 | 3,702,000 | 8.85% | ||
| 5 | Rock Springs Capital Management LP | 492,500 | 1,448,000 | 3.46% | ||
| 6 | VANGUARD GROUP INC | 424,112 | 1,247,000 | 2.98% | ||
| 7 | BlackRock Fund Advisors | 380,645 | 1,119,000 | 2.68% | ||
| 8 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 172,989 | 509,000 | 1.22% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 104,386 | 307,000 | 0.73% | ||
| 10 | GOLDMAN SACHS GROUP INC | 75,051 | 221,000 | 0.53% | ||
| 11 | MORGAN STANLEY | 68,867 | 202,000 | 0.48% | ||
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 47,830 | 140,000 | 0.33% | ||
| 13 | MILLENNIUM MANAGEMENT LLC | 32,984 | 97,000 | 0.23% | ||
| 14 | CREDIT SUISSE AG/ | 23,824 | 70,000 | 0.17% | ||
| 15 | VAN ECK ASSOCIATES CORP | 23,745 | 70,000 | 0.17% | ||
| 16 | ProShare Advisors LLC | 15,361 | 45,000 | 0.11% | ||
| 17 | NORTHERN TRUST CORP | 14,948 | 44,000 | 0.11% | ||
| 18 | Bank of New York Mellon Corp | 11,195 | 33,000 | 0.08% | ||
| 19 | WEDBUSH SECURITIES INC | 10,000 | 29,000 | 0.07% | ||
| 20 | Tower Research Capital LLC (TRC) | 9,541 | 28,000 | 0.07% | ||
| 21 | Psagot Value Holdings Ltd. | 9,078 | 27,000 | 0.06% | ||
| 22 | BANK OF AMERICA CORP /DE/ | 9,030 | 27,000 | 0.06% | ||
| 23 | DEUTSCHE BANK AG\ | 8,855 | 26,000 | 0.06% | ||
| 24 | BLACKROCK ADVISORS LLC | 6,599 | 19,000 | 0.05% | ||
| 25 | PENSERRA CAPITAL MANAGEMENT LLC | 5,848 | 17,000 | 0.04% | ||
| 26 | BARCLAYS PLC | 4,722 | 14,000 | 0.03% | ||
| 27 | CITIGROUP INC | 3,929 | 12,000 | 0.03% | ||
| 28 | BlackRock Investment Management, LLC | 3,229 | 9,000 | 0.02% | ||
| 29 | ROYAL BANK OF CANADA | 3,000 | 9,000 | 0.02% | ||
| 30 | UBS Group AG | 3,110 | 9,000 | 0.02% | ||
| 31 | INTEGRATED WEALTH MANAGEMENT | 1,500 | 4,000 | 0.01% | ||
| 32 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 614 | 2,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
