| 1 |
MPM ASSET MANAGEMENT LLC |
5,736,296 |
11,186,000 |
43.01% |
|
|
| 2 |
FMR LLC |
3,189,747 |
6,220,000 |
23.91% |
|
|
| 3 |
Abingworth LLP |
2,080,595 |
3,953,000 |
15.20% |
|
|
| 4 |
WELLINGTON MANAGEMENT GROUP LLP |
629,108 |
1,226,000 |
4.71% |
|
|
| 5 |
Rock Springs Capital Management LP |
492,500 |
960,000 |
3.69% |
|
|
| 6 |
VANGUARD GROUP INC |
301,465 |
588,000 |
2.26% |
|
|
| 7 |
Anson Funds Management LP |
205,380 |
400,000 |
1.54% |
|
|
| 8 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
172,989 |
337,000 |
1.30% |
|
|
| 9 |
BlackRock Institutional Trust Company, N.A. |
127,903 |
249,000 |
0.96% |
|
|
| 10 |
MORGAN STANLEY |
117,674 |
230,000 |
0.88% |
|
|
| 11 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
64,576 |
126,000 |
0.48% |
|
|
| 12 |
GOLDMAN SACHS GROUP INC |
58,954 |
115,000 |
0.44% |
|
|
| 13 |
GEODE CAPITAL MANAGEMENT, LLC |
48,086 |
93,000 |
0.36% |
|
|
| 14 |
BlackRock Fund Advisors |
45,457 |
89,000 |
0.34% |
|
|
| 15 |
Virtu KCG Holdings LLC |
31,144 |
61,000 |
0.23% |
|
|
| 16 |
MILLENNIUM MANAGEMENT LLC |
28,778 |
56,000 |
0.22% |
|
|
| 17 |
NORTHERN TRUST CORP |
11,618 |
23,000 |
0.09% |
|
|
| 18 |
WEDBUSH SECURITIES INC |
11,500 |
22,000 |
0.08% |
|
|
| 19 |
Paloma Partners Management Co |
11,007 |
21,000 |
0.08% |
|
|
| 20 |
BARCLAYS PLC |
7,680 |
14,000 |
0.05% |
|
|
| 21 |
BLACKROCK ADVISORS LLC |
6,599 |
13,000 |
0.05% |
|
|
| 22 |
UBS Group AG |
5,315 |
10,000 |
0.04% |
|
|
| 23 |
BlackRock Investment Management, LLC |
3,229 |
6,000 |
0.02% |
|
|
| 24 |
ROYAL BANK OF CANADA |
3,000 |
6,000 |
0.02% |
|
|
| 25 |
Tower Research Capital LLC (TRC) |
800 |
2,000 |
0.01% |
|
|
| 26 |
BANK OF AMERICA CORP /DE/ |
1,243 |
2,000 |
0.01% |
|
|
| 27 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
614 |
1,000 |
0.00% |
|
|
| 28 |
INDEPENDENT ADVISOR ALLIANCE |
450 |
878 |
0.00% |
|
|
| 29 |
JPMORGAN CHASE & CO |
144 |
0 |
0.00% |
|
|
