| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,150,700 | 27,611,000 | 43.47% | ||
| 2 | VHCP Management, LLC | 527,842 | 12,666,000 | 19.94% | ||
| 3 | BAKER BROS. ADVISORS LP | 395,882 | 9,499,000 | 14.96% | ||
| 4 | RA CAPITAL MANAGEMENT, L.P. | 263,921 | 6,333,000 | 9.97% | ||
| 5 | EcoR1 Capital, LLC | 100,709 | 2,417,000 | 3.81% | ||
| 6 | MILLENNIUM MANAGEMENT LLC | 61,942 | 1,486,000 | 2.34% | ||
| 7 | TURNER INVESTMENTS LLC | 41,756 | 1,002,000 | 1.58% | ||
| 8 | Cormorant Asset Management, LP | 28,650 | 687,000 | 1.08% | ||
| 9 | NEA Management Company, LLC | 26,894 | 645,000 | 1.02% | ||
| 10 | DAFNA Capital Management LLC | 26,390 | 633,000 | 1.00% | ||
| 11 | Ghost Tree Capital, LLC | 20,325 | 488,000 | 0.77% | ||
| 12 | Tower Research Capital LLC (TRC) | 947 | 23,000 | 0.04% | ||
| 13 | UBS Group AG | 868 | 21,000 | 0.03% | ||
| 14 | AMERICAN INTERNATIONAL GROUP, INC. | 25 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.