| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,150,700 | 9,792,000 | 29.08% | ||
| 2 | VIVO CAPITAL, LLC | 527,842 | 4,492,000 | 13.34% | ||
| 3 | BAKER BROS. ADVISORS LP | 496,901 | 4,229,000 | 12.56% | ||
| 4 | NEA Management Company, LLC | 452,167 | 3,848,000 | 11.43% | ||
| 5 | VHCP MANAGEMENT II, LLC | 369,490 | 3,144,000 | 9.34% | ||
| 6 | QVT Financial LP | 263,921 | 1,833,000 | 5.44% | ||
| 7 | FORESITE CAPITAL MANAGEMENT III, LLC | 197,072 | 1,677,000 | 4.98% | ||
| 8 | VHCP Management, LLC | 158,352 | 1,348,000 | 4.00% | ||
| 9 | BOXER CAPITAL, LLC | 139,899 | 1,191,000 | 3.54% | ||
| 10 | RA CAPITAL MANAGEMENT, L.P. | 114,039 | 970,000 | 2.88% | ||
| 11 | Ghost Tree Capital, LLC | 46,622 | 397,000 | 1.18% | ||
| 12 | DEUTSCHE BANK AG\ | 23,387 | 199,000 | 0.59% | ||
| 13 | ACUTA CAPITAL PARTNERS, LLC | 23,169 | 197,000 | 0.59% | ||
| 14 | UBS Group AG | 22,228 | 189,000 | 0.56% | ||
| 15 | SABBY MANAGEMENT, LLC | 17,428 | 148,000 | 0.44% | ||
| 16 | Tower Research Capital LLC (TRC) | 853 | 7,000 | 0.02% | ||
| 17 | ArrowMark Colorado Holdings LLC | 800 | 7,000 | 0.02% | ||
| 18 | MORGAN STANLEY | 229 | 2,000 | 0.01% | ||
| 19 | ADVISOR GROUP, INC. | 25 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
