| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,150,700 | 16,110,000 | 31.58% | ||
| 2 | VIVO CAPITAL, LLC | 527,842 | 7,390,000 | 14.49% | ||
| 3 | BAKER BROS. ADVISORS LP | 395,882 | 5,542,000 | 10.86% | ||
| 4 | VHCP MANAGEMENT II, LLC | 369,490 | 5,173,000 | 10.14% | ||
| 5 | FORESITE CAPITAL MANAGEMENT III, LLC | 263,921 | 3,695,000 | 7.24% | ||
| 6 | QVT Financial LP | 263,921 | 3,205,000 | 6.28% | ||
| 7 | RA CAPITAL MANAGEMENT, L.P. | 257,721 | 2,598,000 | 5.09% | ||
| 8 | VHCP Management, LLC | 158,352 | 2,217,000 | 4.35% | ||
| 9 | BOXER CAPITAL, LLC | 139,899 | 1,959,000 | 3.84% | ||
| 10 | EcoR1 Capital, LLC | 92,303 | 1,292,000 | 2.53% | ||
| 11 | Ghost Tree Capital, LLC | 46,622 | 653,000 | 1.28% | ||
| 12 | SABBY MANAGEMENT, LLC | 40,705 | 606,000 | 1.19% | ||
| 13 | ACUTA CAPITAL PARTNERS, LLC | 18,250 | 236,000 | 0.46% | ||
| 14 | DEUTSCHE BANK AG\ | 23,387 | 235,000 | 0.46% | ||
| 15 | DAFNA Capital Management LLC | 4,741 | 66,000 | 0.13% | ||
| 16 | UBS Group AG | 1,754 | 18,000 | 0.04% | ||
| 17 | MORGAN STANLEY | 1,768 | 18,000 | 0.04% | ||
| 18 | TURNER INVESTMENTS LLC | 345 | 4,000 | 0.01% | ||
| 19 | AMERICAN INTERNATIONAL GROUP, INC. | 25 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
