| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,150,700 | 8,101,000 | 29.43% | ||
| 2 | VIVO CAPITAL, LLC | 527,842 | 3,716,000 | 13.50% | ||
| 3 | BAKER BROS. ADVISORS LP | 496,901 | 3,498,000 | 12.71% | ||
| 4 | NEA Management Company, LLC | 452,167 | 3,183,000 | 11.56% | ||
| 5 | VHCP MANAGEMENT II, LLC | 369,490 | 2,601,000 | 9.45% | ||
| 6 | QVT Financial LP | 258,121 | 1,454,000 | 5.28% | ||
| 7 | FORESITE CAPITAL MANAGEMENT III, LLC | 197,072 | 1,387,000 | 5.04% | ||
| 8 | VHCP Management, LLC | 158,352 | 1,115,000 | 4.05% | ||
| 9 | BOXER CAPITAL, LLC | 139,899 | 985,000 | 3.58% | ||
| 10 | RA CAPITAL MANAGEMENT, L.P. | 101,439 | 714,000 | 2.59% | ||
| 11 | Ghost Tree Capital, LLC | 46,622 | 328,000 | 1.19% | ||
| 12 | DEUTSCHE BANK AG\ | 23,387 | 164,000 | 0.60% | ||
| 13 | UBS Group AG | 21,702 | 152,000 | 0.55% | ||
| 14 | SABBY MANAGEMENT, LLC | 17,428 | 120,000 | 0.44% | ||
| 15 | ROYAL BANK OF CANADA | 600 | 4,000 | 0.01% | ||
| 16 | MORGAN STANLEY | 229 | 2,000 | 0.01% | ||
| 17 | ADVISOR GROUP, INC. | 25 | 0 | 0.00% | ||
| 18 | CITIGROUP INC | 30 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
