| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,150,700 | 16,685,000 | 33.90% | ||
| 2 | BAKER BROS. ADVISORS LP | 395,882 | 5,740,000 | 11.66% | ||
| 3 | VHCP MANAGEMENT II, LLC | 369,490 | 5,358,000 | 10.89% | ||
| 4 | RA CAPITAL MANAGEMENT, L.P. | 263,921 | 3,827,000 | 7.78% | ||
| 5 | FORESITE CAPITAL MANAGEMENT III, LLC | 263,921 | 3,827,000 | 7.78% | ||
| 6 | QVT Financial LP | 263,921 | 3,641,000 | 7.40% | ||
| 7 | VHCP Management, LLC | 158,352 | 2,296,000 | 4.66% | ||
| 8 | BOXER CAPITAL, LLC | 139,899 | 2,029,000 | 4.12% | ||
| 9 | NEA Management Company, LLC | 121,970 | 1,769,000 | 3.59% | ||
| 10 | EcoR1 Capital, LLC | 100,750 | 1,461,000 | 2.97% | ||
| 11 | MILLENNIUM MANAGEMENT LLC | 51,221 | 743,000 | 1.51% | ||
| 12 | Ghost Tree Capital, LLC | 47,116 | 683,000 | 1.39% | ||
| 13 | TURNER INVESTMENTS LLC | 32,274 | 468,000 | 0.95% | ||
| 14 | DEUTSCHE BANK AG\ | 19,787 | 286,000 | 0.58% | ||
| 15 | ACUTA CAPITAL PARTNERS, LLC | 17,023 | 247,000 | 0.50% | ||
| 16 | DAFNA Capital Management LLC | 8,341 | 121,000 | 0.25% | ||
| 17 | BANK OF AMERICA CORP /DE/ | 1,504 | 22,000 | 0.04% | ||
| 18 | UBS Group AG | 720 | 10,000 | 0.02% | ||
| 19 | Tower Research Capital LLC (TRC) | 510 | 7,000 | 0.01% | ||
| 20 | AMERICAN INTERNATIONAL GROUP, INC. | 25 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
