| 1 |
VIVO CAPITAL, LLC |
1,599,592 |
26,825,000 |
52.48% |
|
|
| 2 |
RA CAPITAL MANAGEMENT, L.P. |
291,700 |
4,892,000 |
9.57% |
|
|
| 3 |
SABBY MANAGEMENT, LLC |
259,643 |
4,354,000 |
8.52% |
|
|
| 4 |
EcoR1 Capital, LLC |
189,545 |
3,179,000 |
6.22% |
|
|
| 5 |
SPHERA FUNDS MANAGEMENT LTD. |
147,514 |
2,474,000 |
4.84% |
|
|
| 6 |
Lombard Odier Asset Management (USA) Corp |
139,688 |
2,343,000 |
4.58% |
|
|
| 7 |
PERCEPTIVE ADVISORS LLC |
104,920 |
1,759,000 |
3.44% |
|
|
| 8 |
BOXER CAPITAL, LLC |
93,331 |
1,565,000 |
3.06% |
|
|
| 9 |
MONASHEE INVESTMENT MANAGEMENT LLC |
84,680 |
1,420,000 |
2.78% |
|
PRN |
| 10 |
VANGUARD GROUP INC |
34,128 |
573,000 |
1.12% |
|
|
| 11 |
WELLINGTON MANAGEMENT GROUP LLP |
18,763 |
315,000 |
0.62% |
|
|
| 12 |
DEUTSCHE BANK AG\ |
16,303 |
273,000 |
0.53% |
|
|
| 13 |
BlackRock Institutional Trust Company, N.A. |
15,541 |
261,000 |
0.51% |
|
|
| 14 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
14,938 |
251,000 |
0.49% |
|
|
| 15 |
Ancora Advisors LLC |
13,346 |
224,000 |
0.44% |
|
|
| 16 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
10,000 |
168,000 |
0.33% |
|
|
| 17 |
BlackRock Fund Advisors |
3,378 |
57,000 |
0.11% |
|
|
| 18 |
GROUP ONE TRADING LLC |
3,378 |
57,000 |
0.11% |
|
|
| 19 |
BELLEVUE GROUP AG |
3,333 |
56,000 |
0.11% |
|
|
| 20 |
CUTLER GROUP LLC / CA |
1,189 |
19,000 |
0.04% |
|
|
| 21 |
MORGAN STANLEY |
1,000 |
17,000 |
0.03% |
|
|
| 22 |
WELLS FARGO & COMPANY/MN |
746 |
12,000 |
0.02% |
|
|
| 23 |
BLACKROCK ADVISORS LLC |
304 |
5,000 |
0.01% |
|
|
| 24 |
BlackRock Investment Management, LLC |
245 |
4,000 |
0.01% |
|
|
| 25 |
CITIGROUP INC |
175 |
3,000 |
0.01% |
|
|
| 26 |
Walleye Trading LLC |
114 |
2,000 |
0.00% |
|
|
| 27 |
MSI Financial Services Inc |
133 |
2,000 |
0.00% |
|
|
| 28 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
46 |
1,000 |
0.00% |
|
|
| 29 |
IFP ADVISORS, INC |
40 |
1,000 |
0.00% |
|
|
| 30 |
MARK SHEPTOFF FINANCIAL PLANNING, LLC |
33 |
1,000 |
0.00% |
|
|
| 31 |
Tower Research Capital LLC (TRC) |
87 |
1,000 |
0.00% |
|
|
| 32 |
BARCLAYS PLC |
4 |
0 |
0.00% |
|
|
| 33 |
BANK OF AMERICA CORP /DE/ |
26 |
0 |
0.00% |
|
|
| 34 |
Creative Planning |
2 |
0 |
0.00% |
|
|
| 35 |
AMERICAN INTERNATIONAL GROUP, INC. |
13 |
0 |
0.00% |
|
|
| 36 |
UBS Group AG |
5 |
0 |
0.00% |
|
|
