| 1 |
Third Rock Ventures, LLC |
4,841,591 |
63,812,000 |
41.75% |
|
|
| 2 |
Flagship Ventures 2007 General Partner LLC |
1,907,008 |
25,134,000 |
16.44% |
|
|
| 3 |
FMR LLC |
1,827,512 |
24,087,000 |
15.76% |
|
|
| 4 |
FRANKLIN RESOURCES INC |
1,027,600 |
13,544,000 |
8.86% |
|
|
| 5 |
Broadfin Capital, LLC |
857,715 |
11,305,000 |
7.40% |
|
|
| 6 |
JPMORGAN CHASE & CO |
253,450 |
3,340,000 |
2.19% |
|
|
| 7 |
SABBY MANAGEMENT, LLC |
143,974 |
1,898,000 |
1.24% |
|
|
| 8 |
BlackRock Fund Advisors |
101,961 |
1,344,000 |
0.88% |
|
|
| 9 |
PRINCIPAL FINANCIAL GROUP INC |
95,300 |
1,256,000 |
0.82% |
|
|
| 10 |
VANGUARD GROUP INC |
86,462 |
1,139,000 |
0.75% |
|
|
| 11 |
State of New Jersey Common Pension Fund D |
75,000 |
989,000 |
0.65% |
|
|
| 12 |
STATE STREET CORP |
59,011 |
778,000 |
0.51% |
|
|
| 13 |
TCW GROUP INC |
49,528 |
654,000 |
0.43% |
|
|
| 14 |
Bank of New York Mellon Corp |
49,605 |
654,000 |
0.43% |
|
|
| 15 |
NORTHERN TRUST CORP |
46,490 |
612,000 |
0.40% |
|
|
| 16 |
BlackRock Institutional Trust Company, N.A. |
41,963 |
553,000 |
0.36% |
|
|
| 17 |
NJ State Employees Deferred Compensation Plan |
25,000 |
330,000 |
0.22% |
|
|
| 18 |
GEODE CAPITAL MANAGEMENT, LLC |
23,791 |
313,000 |
0.20% |
|
|
| 19 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
16,422 |
216,000 |
0.14% |
|
|
| 20 |
BlackRock Investment Management, LLC |
13,451 |
177,000 |
0.12% |
|
|
| 21 |
BANQUE PICTET & CIE SA |
11,714 |
154,000 |
0.10% |
|
|
| 22 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
8,300 |
109,000 |
0.07% |
|
|
| 23 |
Nationwide Fund Advisors |
8,074 |
106,000 |
0.07% |
|
|
| 24 |
TEACHERS ADVISORS, LLC |
6,131 |
81,000 |
0.05% |
|
|
| 25 |
PARADIGM ASSET MANAGEMENT CO LLC |
5,750 |
75,785 |
0.05% |
|
|
| 26 |
MORGAN STANLEY |
3,417 |
45,000 |
0.03% |
|
|
| 27 |
AMERICAN INTERNATIONAL GROUP, INC. |
2,998 |
39,514 |
0.03% |
|
|
| 28 |
BLACKROCK ADVISORS LLC |
1,919 |
25,000 |
0.02% |
|
|
| 29 |
DEUTSCHE BANK AG\ |
1,203 |
15,000 |
0.01% |
|
|
| 30 |
Tower Research Capital LLC (TRC) |
861 |
11,000 |
0.01% |
|
|
| 31 |
ALLIANCEBERNSTEIN L.P. |
600 |
8,000 |
0.01% |
|
|
| 32 |
UBS AG |
532 |
7,000 |
0.00% |
|
|
| 33 |
BANK OF AMERICA CORP /DE/ |
430 |
6,000 |
0.00% |
|
|
| 34 |
VIRTUS CAPITAL ADVISERS, LLC |
391 |
5,000 |
0.00% |
|
|
| 35 |
BARCLAYS PLC |
393 |
5,000 |
0.00% |
|
|
| 36 |
WELLS FARGO & COMPANY/MN |
426 |
5,000 |
0.00% |
|
|
| 37 |
BANK OF MONTREAL /CAN/ |
120 |
2,000 |
0.00% |
|
|
| 38 |
CITIGROUP INC |
156 |
2,000 |
0.00% |
|
|
| 39 |
BNP PARIBAS FINANCIAL MARKETS |
93 |
1,226 |
0.00% |
|
|
