| 1 |
FMR LLC |
2,863,594 |
8,619,000 |
25.60% |
|
|
| 2 |
FRANKLIN RESOURCES INC |
2,314,586 |
6,967,000 |
20.69% |
|
|
| 3 |
Flagship Ventures 2007 General Partner LLC |
1,907,008 |
5,740,000 |
17.05% |
|
|
| 4 |
FLAGSHIP VENTURES FUND IV GENERAL PARTNER LLC |
1,466,417 |
4,414,000 |
13.11% |
|
|
| 5 |
Redmile Group, LLC |
875,857 |
2,636,000 |
7.83% |
|
|
| 6 |
FEDERATED HERMES, INC. |
775,000 |
2,333,000 |
6.93% |
|
|
| 7 |
VANGUARD GROUP INC |
204,207 |
614,000 |
1.82% |
|
|
| 8 |
SABBY MANAGEMENT, LLC |
194,041 |
584,000 |
1.73% |
|
|
| 9 |
BlackRock Institutional Trust Company, N.A. |
149,618 |
450,000 |
1.34% |
|
|
| 10 |
Rotella Capital Management, Inc. |
112,445 |
338,000 |
1.00% |
|
|
| 11 |
Bank of New York Mellon Corp |
80,087 |
241,000 |
0.72% |
|
|
| 12 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
50,000 |
151,000 |
0.45% |
|
|
| 13 |
GEODE CAPITAL MANAGEMENT, LLC |
46,687 |
140,000 |
0.42% |
|
|
| 14 |
MILLENNIUM MANAGEMENT LLC |
36,272 |
109,000 |
0.32% |
|
|
| 15 |
BlackRock Fund Advisors |
33,226 |
100,000 |
0.30% |
|
|
| 16 |
Connor, Clark & Lunn Investment Management Ltd. |
25,500 |
77,000 |
0.23% |
|
|
| 17 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
14,748 |
44,000 |
0.13% |
|
|
| 18 |
GOLDMAN SACHS GROUP INC |
10,584 |
32,000 |
0.10% |
|
|
| 19 |
FIDUCIARY TRUST CO |
10,000 |
30,000 |
0.09% |
|
|
| 20 |
THOMPSON DAVIS & CO., INC. |
6,000 |
18,000 |
0.05% |
|
|
| 21 |
UBS Group AG |
3,642 |
11,000 |
0.03% |
|
|
| 22 |
GROUP ONE TRADING LLC |
2,400 |
7,000 |
0.02% |
|
|
| 23 |
BlackRock Investment Management, LLC |
1,793 |
5,000 |
0.01% |
|
|
| 24 |
ROYAL BANK OF CANADA |
600 |
2,000 |
0.01% |
|
|
| 25 |
CITIGROUP INC |
600 |
2,000 |
0.01% |
|
|
| 26 |
AMERICAN INTERNATIONAL GROUP, INC. |
250 |
1,000 |
0.00% |
|
|
| 27 |
Tower Research Capital LLC (TRC) |
437 |
1,000 |
0.00% |
|
|
| 28 |
MORGAN STANLEY |
300 |
1,000 |
0.00% |
|
|
| 29 |
REILLY FINANCIAL ADVISORS, LLC |
100 |
0 |
0.00% |
|
|
