| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 6,976,162 | 23,370,000 | 14.09% | ||
| 2 | PUTNAM INVESTMENTS LLC | 5,507,200 | 18,449,000 | 11.12% | ||
| 3 | Broadfin Capital, LLC | 5,213,979 | 17,467,000 | 10.53% | ||
| 4 | VANGUARD GROUP INC | 3,486,484 | 11,679,000 | 7.04% | ||
| 5 | NATIXIS | 3,148,916 | 10,549,000 | 6.36% | ||
| 6 | BlackRock Fund Advisors | 2,246,640 | 7,526,000 | 4.54% | ||
| 7 | JENNISON ASSOCIATES LLC | 2,170,164 | 7,270,000 | 4.38% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 2,148,240 | 7,197,000 | 4.34% | ||
| 9 | DEUTSCHE BANK AG\ | 2,021,347 | 6,769,000 | 4.08% | ||
| 10 | JPMORGAN CHASE & CO | 1,998,050 | 6,693,000 | 4.04% | ||
| 11 | FMR LLC | 1,684,581 | 5,643,000 | 3.40% | ||
| 12 | Palo Alto Investors LP | 1,257,748 | 4,213,000 | 2.54% | ||
| 13 | STATE STREET CORP | 1,191,342 | 3,990,000 | 2.41% | ||
| 14 | Alyeska Investment Group, L.P. | 1,124,538 | 3,767,000 | 2.27% | ||
| 15 | Atria Investments, Inc | 10 | 3,100,000 | 1.87% | ||
| 16 | NORTHERN TRUST CORP | 920,107 | 3,082,000 | 1.86% | ||
| 17 | Point72 Asset Management, L.P. | 670,600 | 2,247,000 | 1.35% | ||
| 18 | GEODE CAPITAL MANAGEMENT, LLC | 616,034 | 2,063,000 | 1.24% | ||
| 19 | WALL STREET ASSOCIATES | 500,000 | 1,675,000 | 1.01% | ||
| 20 | DIMENSIONAL FUND ADVISORS LP | 410,054 | 1,374,000 | 0.83% | ||
| 21 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 396,868 | 1,330,000 | 0.80% | ||
| 22 | GUARDIAN LIFE INSURANCE CO OF AMERICA | 371,759 | 1,245,000 | 0.75% | ||
| 23 | GOLDMAN SACHS GROUP INC | 351,297 | 1,177,000 | 0.71% | ||
| 24 | Bank of New York Mellon Corp | 325,719 | 1,091,000 | 0.66% | ||
| 25 | BlackRock Investment Management, LLC | 304,334 | 1,020,000 | 0.62% | ||
| 26 | TIAA CREF INVESTMENT MANAGEMENT LLC | 299,891 | 1,005,000 | 0.61% | ||
| 27 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 215,400 | 722,000 | 0.44% | Call | |
| 28 | MYCIO WEALTH PARTNERS, LLC | 200,000 | 670,000 | 0.40% | ||
| 29 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 195,900 | 656,000 | 0.40% | ||
| 30 | VIRTUS CAPITAL ADVISERS, LLC | 194,872 | 653,000 | 0.39% | ||
| 31 | GROUP ONE TRADING LLC | 170,161 | 570,000 | 0.34% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 167,500 | 561,000 | 0.34% | Put | |
| 33 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 155,604 | 521,000 | 0.31% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 151,729 | 509,000 | 0.31% | ||
| 35 | CREDIT SUISSE AG/ | 140,979 | 472,000 | 0.28% | ||
| 36 | SABBY MANAGEMENT, LLC | 137,700 | 461,000 | 0.28% | ||
| 37 | TEACHERS ADVISORS, LLC | 125,136 | 419,000 | 0.25% | ||
| 38 | Creative Planning | 104,500 | 350,000 | 0.21% | ||
| 39 | MILLENNIUM MANAGEMENT LLC | 88,111 | 295,000 | 0.18% | ||
| 40 | LEAVELL INVESTMENT MANAGEMENT, INC. | 81,271 | 272,000 | 0.16% | ||
| 41 | RHUMBLINE ADVISERS | 78,959 | 265,000 | 0.16% | ||
| 42 | NEW YORK STATE COMMON RETIREMENT FUND | 78,200 | 262,000 | 0.16% | ||
| 43 | METROPOLITAN LIFE INSURANCE CO/NY | 63,909 | 214,000 | 0.13% | ||
| 44 | AMERICAN INTERNATIONAL GROUP, INC. | 61,148 | 205,000 | 0.12% | ||
| 45 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 59,357 | 199,000 | 0.12% | ||
| 46 | Nationwide Fund Advisors | 56,145 | 188,000 | 0.11% | ||
| 47 | BLACKROCK ADVISORS LLC | 55,910 | 187,000 | 0.11% | ||
| 48 | ALLIANCEBERNSTEIN L.P. | 55,600 | 186,000 | 0.11% | ||
| 49 | AQR CAPITAL MANAGEMENT LLC | 55,122 | 185,000 | 0.11% | ||
| 50 | BALYASNY ASSET MANAGEMENT L.P. | 43,150 | 145,000 | 0.09% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
