| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Broadfin Capital, LLC | 1,545,306 | 12,084,000 | 22.36% | ||
| 2 | Opaleye Management Inc. | 1,058,400 | 8,277,000 | 15.31% | ||
| 3 | JENNISON ASSOCIATES LLC | 841,959 | 6,584,000 | 12.18% | ||
| 4 | VANGUARD GROUP INC | 611,766 | 4,784,000 | 8.85% | ||
| 5 | BlackRock Institutional Trust Company, N.A. | 505,925 | 3,956,000 | 7.32% | ||
| 6 | BlackRock Fund Advisors | 438,580 | 3,430,000 | 6.35% | ||
| 7 | BAILLIE GIFFORD & CO | 360,650 | 2,821,000 | 5.22% | ||
| 8 | QVT Financial LP | 267,608 | 2,093,000 | 3.87% | ||
| 9 | NORTHERN TRUST CORP | 179,886 | 1,407,000 | 2.60% | ||
| 10 | STATE STREET CORP | 163,039 | 1,276,000 | 2.36% | ||
| 11 | GEODE CAPITAL MANAGEMENT, LLC | 143,490 | 1,122,000 | 2.08% | ||
| 12 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 119,000 | 931,000 | 1.72% | ||
| 13 | Alyeska Investment Group, L.P. | 78,575 | 614,000 | 1.14% | ||
| 14 | Bank of New York Mellon Corp | 67,388 | 527,000 | 0.98% | ||
| 15 | BlackRock Investment Management, LLC | 58,792 | 460,000 | 0.85% | ||
| 16 | TIAA CREF INVESTMENT MANAGEMENT LLC | 52,648 | 412,000 | 0.76% | ||
| 17 | LPL Financial LLC | 47,057 | 328,000 | 0.61% | ||
| 18 | CARL DOMINO INC | 34,134 | 267,000 | 0.49% | ||
| 19 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 30,634 | 240,000 | 0.44% | ||
| 20 | MILLENNIUM MANAGEMENT LLC | 25,000 | 196,000 | 0.36% | ||
| 21 | TEACHERS ADVISORS, LLC | 24,924 | 195,000 | 0.36% | ||
| 22 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 23,712 | 186,000 | 0.34% | ||
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 21,600 | 169,000 | 0.31% | Call | |
| 24 | WHITE PINE CAPITAL LLC | 20,000 | 156,000 | 0.29% | ||
| 25 | Spot Trading L.L.C | 18,600 | 145,000 | 0.27% | Call | |
| 26 | VAN ECK ASSOCIATES CORP | 17,589 | 138,000 | 0.26% | ||
| 27 | Psagot Value Holdings Ltd. | 17,130 | 134,000 | 0.25% | ||
| 28 | NEW YORK STATE COMMON RETIREMENT FUND | 15,500 | 121,000 | 0.22% | ||
| 29 | RHUMBLINE ADVISERS | 14,055 | 110,000 | 0.20% | ||
| 30 | GOLDMAN SACHS GROUP INC | 13,941 | 109,000 | 0.20% | ||
| 31 | MORGAN STANLEY | 13,591 | 106,000 | 0.20% | ||
| 32 | HYMAN CHARLES D | 13,000 | 102,000 | 0.19% | ||
| 33 | BLACKROCK ADVISORS LLC | 12,727 | 100,000 | 0.19% | ||
| 34 | Nationwide Fund Advisors | 10,521 | 82,000 | 0.15% | ||
| 35 | AMERICAN INTERNATIONAL GROUP, INC. | 9,873 | 77,000 | 0.14% | ||
| 36 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 6,321 | 49,000 | 0.09% | ||
| 37 | STRS OHIO | 5,400 | 42,000 | 0.08% | ||
| 38 | DEUTSCHE BANK AG\ | 4,644 | 36,000 | 0.07% | ||
| 39 | BNP PARIBAS FINANCIAL MARKETS | 3,337 | 26,095 | 0.05% | ||
| 40 | UBS Group AG | 2,950 | 23,000 | 0.04% | ||
| 41 | VICTORY CAPITAL MANAGEMENT INC | 2,765 | 22,000 | 0.04% | ||
| 42 | ROYAL BANK OF CANADA | 2,814 | 22,000 | 0.04% | ||
| 43 | Tower Research Capital LLC (TRC) | 1,915 | 15,000 | 0.03% | ||
| 44 | WELLS FARGO & COMPANY/MN | 1,941 | 15,000 | 0.03% | ||
| 45 | Kavar Capital Partners, LLC | 1,500 | 11,000 | 0.02% | ||
| 46 | CITIGROUP INC | 1,324 | 10,000 | 0.02% | ||
| 47 | Spot Trading L.L.C | 1,200 | 9,000 | 0.02% | Put | |
| 48 | Brick & Kyle, Associates | 1,000 | 8,000 | 0.01% | ||
| 49 | TCI Wealth Advisors, Inc. | 1,000 | 8,000 | 0.01% | ||
| 50 | Creative Planning | 940 | 7,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
