| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Broadfin Capital, LLC | 1,025,000 | 8,262,000 | 18.02% | ||
| 2 | JENNISON ASSOCIATES LLC | 968,792 | 7,799,000 | 17.01% | ||
| 3 | Opaleye Management Inc. | 850,000 | 6,851,000 | 14.94% | ||
| 4 | PERCEPTIVE ADVISORS LLC | 639,225 | 5,146,000 | 11.22% | ||
| 5 | VANGUARD GROUP INC | 504,526 | 4,061,000 | 8.86% | ||
| 6 | BAILLIE GIFFORD & CO | 360,650 | 2,903,000 | 6.33% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 316,439 | 2,550,000 | 5.56% | ||
| 8 | SPHERA FUNDS MANAGEMENT LTD. | 175,000 | 1,411,000 | 3.08% | ||
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 125,439 | 1,008,000 | 2.20% | ||
| 10 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 79,000 | 636,000 | 1.39% | ||
| 11 | Alyeska Investment Group, L.P. | 70,228 | 566,000 | 1.23% | ||
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 51,216 | 412,000 | 0.90% | ||
| 13 | LPL Financial LLC | 47,697 | 386,000 | 0.84% | ||
| 14 | BlackRock Fund Advisors | 42,840 | 345,000 | 0.75% | ||
| 15 | Janney Montgomery Scott LLC | 41,923 | 338,000 | 0.74% | ||
| 16 | CREDIT SUISSE AG/ | 38,992 | 314,000 | 0.68% | ||
| 17 | CARL DOMINO INC | 34,134 | 275,000 | 0.60% | ||
| 18 | Geduld E E | 32,500 | 262,000 | 0.57% | ||
| 19 | NORTHERN TRUST CORP | 29,477 | 238,000 | 0.52% | ||
| 20 | RENAISSANCE TECHNOLOGIES LLC | 25,200 | 203,000 | 0.44% | ||
| 21 | MILLENNIUM MANAGEMENT LLC | 24,108 | 194,000 | 0.42% | ||
| 22 | GOLDMAN SACHS GROUP INC | 21,862 | 176,000 | 0.38% | ||
| 23 | Spot Trading L.L.C | 20,000 | 161,000 | 0.35% | Call | |
| 24 | WHITE PINE CAPITAL LLC | 20,000 | 161,000 | 0.35% | ||
| 25 | STATE STREET CORP | 20,000 | 160,000 | 0.35% | ||
| 26 | VAN ECK ASSOCIATES CORP | 16,861 | 136,000 | 0.30% | ||
| 27 | Spark Investment Management LLC | 15,400 | 124,000 | 0.27% | ||
| 28 | BlueCrest Capital Management Ltd | 14,901 | 120,000 | 0.26% | ||
| 29 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 13,300 | 107,000 | 0.23% | Put | |
| 30 | Bank of New York Mellon Corp | 13,015 | 105,000 | 0.23% | ||
| 31 | HYMAN CHARLES D | 13,000 | 105,000 | 0.23% | ||
| 32 | UBS Group AG | 12,405 | 100,000 | 0.22% | ||
| 33 | MORGAN STANLEY | 7,876 | 63,000 | 0.14% | ||
| 34 | Ionic Capital Management LLC | 7,500 | 60,000 | 0.13% | ||
| 35 | BLACKROCK ADVISORS LLC | 3,825 | 31,000 | 0.07% | ||
| 36 | BlackRock Investment Management, LLC | 2,837 | 23,000 | 0.05% | ||
| 37 | WELLS FARGO & COMPANY/MN | 1,850 | 15,000 | 0.03% | ||
| 38 | CITIGROUP INC | 1,700 | 14,000 | 0.03% | ||
| 39 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 1,447 | 12,000 | 0.03% | ||
| 40 | Brick & Kyle, Associates | 1,000 | 8,000 | 0.02% | ||
| 41 | TCI Wealth Advisors, Inc. | 1,000 | 8,000 | 0.02% | ||
| 42 | Creative Planning | 940 | 8,000 | 0.02% | ||
| 43 | THOMPSON DAVIS & CO., INC. | 250 | 2,000 | 0.00% | ||
| 44 | Tower Research Capital LLC (TRC) | 96 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
