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Institutional Investment Manager
ORBIMED ADVISORS LLC
ORBIMED ADVISORS LLC (CIK: 0001055951) incorporated in Delaware, located at 601 Lexington Avenue, New York, NY. Institutional holdings reported to the SEC.

Institutional Holdings (2016Q3)
Portfolio Summary: 140 holdings with a total value of $8,780,843,000.
#
Name
Shares
Value ($)
%
Options
Notes
101 TEVA PHARMACEUTICAL INDS LTD 1,831,400 84,263,000 0.96%
102 Audentes Therapeutics, Inc. 4,801,638 85,517,000 0.97%
103 UNITEDHEALTH GROUP INC 611,800 85,652,000 0.98%
104 CORVUS PHARMACEUTICALS INC COM 5,379,349 88,490,000 1.01%
105 IMPAX LABORATORIES INC 3,787,500 89,764,000 1.02%
106 ILLUMINA INC 495,500 90,013,000 1.03%
107 NEUROCRINE BIOSCIE COM USD0.001 1,815,474 91,936,000 1.05%
108 ZIMMER BIOMET HLDGS INC 717,500 93,289,000 1.06%
109 ARRAY BIOPHARMA INC 14,179,900 95,714,000 1.09%
110 HCA HOLDINGS INC 1,312,200 99,242,000 1.13%
111 JOHNSON & JOHNSON 858,000 101,356,000 1.15%
112 EXPRESS SCRIPTS HLDG CO 1,451,900 102,403,000 1.17%
113 ACHILLION PHARMACEUTICALS IN 13,107,200 106,168,000 1.21%
114 BIOMARIN PHARMACEUTICAL INC 1,151,900 106,574,000 1.21%
115 BRISTOL MYERS SQUIBB CO 2,187,400 117,945,000 1.34%
116 PFIZER INC 3,532,200 119,636,000 1.36%
117 THERMO FISHER SCIENTIFIC INC 816,500 129,872,000 1.48%
118 INTUITIVE SURGICAL INC 187,800 136,123,000 1.55%
119 VERTEX PHARMACEUTICALS INC 1,612,000 140,583,000 1.60%
120 REGENERON PHARMACEUTICALS 355,300 142,838,000 1.63%
121 WELLCARE HEALTH PLANS INC 1,248,000 146,128,000 1.66%
122 MOLINA HEALTHCARE INC 2,634,700 153,656,000 1.75%
123 IRONWOOD PHARMACEUTICALS INC 9,949,000 157,990,000 1.80%
124 GILEAD SCIENCES INC 2,010,700 159,087,000 1.81%
125 PUMA BIOTECHNOLOGY 2,383,525 159,815,000 1.82%
126 LILLY ELI & CO 2,040,500 163,771,000 1.87%
127 EDWARDS LIFESCIENCES CORP 1,373,200 165,553,000 1.89%
128 INCYTE CORP 1,850,178 174,453,000 1.99%
129 AGILENT TECHNOLOGIES INC 3,714,800 174,930,000 1.99%
130 ALLERGAN PLC 778,690 179,340,000 2.04%
131 Wright Medical Group NV 7,356,233 180,448,000 2.06%
132 INTERCEPT PHARMACEUTICALS INCORPORATED 1,120,000 184,341,000 2.10%
133 SHIRE PLC 1,063,351 206,141,000 2.35%
134 MERCK & CO INC 3,506,800 218,859,000 2.49%
135 ABBVIE INC 4,229,900 266,780,000 3.04%
136 CELGENE CORP 2,948,577 308,215,000 3.51%
137 ALEXION PHARMACEUTIC 2,638,011 323,262,000 3.68%
138 AMGEN INC 2,436,700 406,466,000 4.63%
139 BOSTON SCIENTIFIC CORP 17,211,700 409,638,000 4.67%
140 BIOGEN INC 1,333,900 417,551,000 4.76%
Page 3 of 3

Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001172661-16-004318, filed 2016.11.14).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.