| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | ALEXION PHARMACEUTIC | 49,397 | 7,725,000 | 0.32% | ||
| 52 | EXACT SCIENCES CORP | 4,293 | 7,723,000 | 0.32% | Put | |
| 53 | PERRIGO CO PLC | 491 | 7,722,000 | 0.32% | Call | |
| 54 | KITE PHARMA INCORPORATED | 137,099 | 7,634,000 | 0.31% | ||
| 55 | BLUEBIRD BIO INC | 889 | 7,605,000 | 0.31% | Call | |
| 56 | ACADIA PHARMACEUTICALS INC | 2,259 | 7,471,000 | 0.31% | Put | |
| 57 | MEDICINES CO | 5,000,000 | 7,278,000 | 0.30% | ||
| 58 | MYLAN N V | 1,747 | 7,033,000 | 0.29% | Call | |
| 59 | TOKAI PHARMACEUTICALS INC COM | 654,283 | 6,772,000 | 0.28% | ||
| 60 | MANNKIND CORP | 20,875 | 6,701,000 | 0.28% | Put | |
| 61 | BLUEPRINT MEDICINES CORP COM | 308,504 | 6,583,000 | 0.27% | ||
| 62 | GW PHARMACEUTICALS PLC | 71,757 | 6,556,000 | 0.27% | ||
| 63 | BIOMARIN PHARMACEUTICAL INC 0.75 10/15/2018 | 5,000,000 | 6,459,000 | 0.27% | ||
| 64 | ALNYLAM PHARMACEUTICALS INC | 789 | 6,340,000 | 0.26% | Put | |
| 65 | ANADARKO PETE CORP | 1,023 | 6,178,000 | 0.25% | Put | |
| 66 | ANADARKO PETE CORP | 102,300 | 6,178,000 | 0.25% | ||
| 67 | NOVAVAX INC | 8,418 | 5,952,000 | 0.25% | Put | |
| 68 | SAREPTA THERAPEUTICS INC | 1,836 | 5,895,000 | 0.24% | Put | |
| 69 | BARCLAYS BK PLC IPATH S&P MT ETN | 450,500 | 5,861,000 | 0.24% | ||
| 70 | SPARK THERAPEUTICS INC | 1,402 | 5,851,000 | 0.24% | Call | |
| 71 | SPARK THERAPEUTICS INC | 1,379 | 5,755,000 | 0.24% | Put | |
| 72 | THERAPEUTICSMD INC | 9,800 | 5,743,000 | 0.24% | Call | |
| 73 | NEUROCRINE BIOSCIENCES INC | 1,403 | 5,583,000 | 0.23% | Call | |
| 74 | KONINKLIJKE PHILIPS N V | 2,374 | 5,569,000 | 0.23% | Call | |
| 75 | INTRA-CELLULAR THERAPIES INC | 1,378 | 5,518,000 | 0.23% | Call | |
| 76 | OPKO HEALTH INC | 6,456 | 5,429,000 | 0.22% | Put | |
| 77 | HALOZYME THERAPEUTICS INC | 4,014 | 5,391,000 | 0.22% | Call | |
| 78 | EXACT SCIENCES CORP | 289,112 | 5,201,000 | 0.21% | ||
| 79 | OPKO HEALTH INC | 615,157 | 5,173,000 | 0.21% | ||
| 80 | FLUIDIGM CORP DEL COM | 628,260 | 5,095,000 | 0.21% | ||
| 81 | DYNAVAX TECHNOLOGIES CORP | 2,073 | 5,087,000 | 0.21% | Call | |
| 82 | DEPOMED INC | 2,680 | 5,052,000 | 0.21% | Call | |
| 83 | GENOCEA BIOSCIENCES INC | 729,141 | 4,995,000 | 0.21% | ||
| 84 | Nivalis Therapeutics Inc | 384,734 | 4,990,000 | 0.21% | ||
| 85 | HCA HOLDINGS INC | 624 | 4,827,000 | 0.20% | Call | |
| 86 | ACHILLION PHARMACEUTICALS INC | 6,916 | 4,779,000 | 0.20% | Call | |
| 87 | ACADIA PHARMACEUTICALS INC | 1,438 | 4,755,000 | 0.20% | Call | |
| 88 | AVALANCHE BIOTECHNOLOGIES IN | 574,260 | 4,732,000 | 0.19% | ||
| 89 | CELLDEX THERAPEUTICS INC NEW | 4,448 | 4,688,000 | 0.19% | Call | |
| 90 | ISIS PHARMACEUTICALS INC | 1,159 | 4,685,000 | 0.19% | Call | |
| 91 | DERMIRA INC COM | 190,000 | 4,435,000 | 0.18% | ||
| 92 | GILEAD SCIENCES INC | 45,140 | 4,432,000 | 0.18% | ||
| 93 | ARBUTUS BIOPHARMA CORP | 725,007 | 4,415,000 | 0.18% | ||
| 94 | RAPTOR PHARMACEUTICAL CORP | 7,289 | 4,410,000 | 0.18% | Call | |
| 95 | NEUROCRINE BIOSCIENCES INC | 1,267 | 4,397,000 | 0.18% | Put | |
| 96 | INOVIO PHARMACEUTICALS INC | 737,551 | 4,263,000 | 0.18% | ||
| 97 | ZS PHARMA INC | 640 | 4,202,000 | 0.17% | Put | |
| 98 | ENDO INTL PLC | 601 | 4,164,000 | 0.17% | Call | |
| 99 | RADIUS HEALTH INC | 578 | 4,006,000 | 0.17% | Call | |
| 100 | HERON THERAPEUTICS INC COM | 160,323 | 3,912,000 | 0.16% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-15-065626, filed 2015.11.16).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
