| 1 |
First Eagle Investment Management, LLC |
8,719,968 |
16,306,000 |
25.44% |
|
|
| 2 |
BVF INC/IL |
6,566,148 |
12,279,000 |
19.15% |
|
|
| 3 |
Nantahala Capital Management, LLC |
4,285,020 |
8,013,000 |
12.50% |
|
|
| 4 |
VANGUARD GROUP INC |
2,722,487 |
5,091,000 |
7.94% |
|
|
| 5 |
NEA Management Company, LLC |
2,520,316 |
4,713,000 |
7.35% |
|
|
| 6 |
BlackRock Institutional Trust Company, N.A. |
2,034,363 |
3,804,000 |
5.93% |
|
|
| 7 |
RENAISSANCE TECHNOLOGIES LLC |
1,936,544 |
3,621,000 |
5.65% |
|
|
| 8 |
D. E. Shaw & Co., Inc. |
1,017,553 |
1,903,000 |
2.97% |
|
|
| 9 |
FMR LLC |
959,601 |
1,794,000 |
2.80% |
|
|
| 10 |
STONERIDGE INVESTMENT PARTNERS LLC |
345,526 |
646,000 |
1.01% |
|
|
| 11 |
GEODE CAPITAL MANAGEMENT, LLC |
321,376 |
600,000 |
0.94% |
|
|
| 12 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
303,993 |
568,000 |
0.89% |
|
|
| 13 |
DIMENSIONAL FUND ADVISORS LP |
276,129 |
516,000 |
0.80% |
|
|
| 14 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
227,250 |
425,000 |
0.66% |
|
|
| 15 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
225,900 |
422,000 |
0.66% |
|
|
| 16 |
State of New Jersey Common Pension Fund D |
223,774 |
418,000 |
0.65% |
|
|
| 17 |
NJ State Employees Deferred Compensation Plan |
190,000 |
355,000 |
0.55% |
|
|
| 18 |
BlackRock Fund Advisors |
151,185 |
283,000 |
0.44% |
|
|
| 19 |
ALGERT GLOBAL LLC |
119,790 |
224,000 |
0.35% |
|
|
| 20 |
NEW YORK STATE COMMON RETIREMENT FUND |
111,428 |
208,000 |
0.32% |
|
|
| 21 |
MILLENNIUM MANAGEMENT LLC |
110,455 |
207,000 |
0.32% |
|
|
| 22 |
NORTHERN TRUST CORP |
105,964 |
198,000 |
0.31% |
|
|
| 23 |
TWO SIGMA ADVISERS, LP |
105,802 |
197,000 |
0.31% |
|
|
| 24 |
Connor, Clark & Lunn Investment Management Ltd. |
89,300 |
167,000 |
0.26% |
|
|
| 25 |
Bank of New York Mellon Corp |
85,550 |
160,000 |
0.25% |
|
|
| 26 |
EAGLE GLOBAL ADVISORS LLC |
68,810 |
129,000 |
0.20% |
|
|
| 27 |
A.R.T. Advisors, LLC |
53,142 |
99,000 |
0.15% |
|
|
| 28 |
GOLDMAN SACHS GROUP INC |
45,504 |
85,000 |
0.13% |
|
|
| 29 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
37,400 |
70,000 |
0.11% |
Call |
|
| 30 |
Spark Investment Management LLC |
37,200 |
69,000 |
0.11% |
|
|
| 31 |
Nine Chapters Capital Management LLC |
34,300 |
64,000 |
0.10% |
|
|
| 32 |
STATE STREET CORP |
33,095 |
61,000 |
0.10% |
|
|
| 33 |
OPPENHEIMER & CO INC |
23,000 |
43,000 |
0.07% |
|
|
| 34 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
21,000 |
40,000 |
0.06% |
|
|
| 35 |
TWO SIGMA INVESTMENTS, LP |
19,518 |
36,000 |
0.06% |
|
|
| 36 |
CREDIT SUISSE AG/ |
17,779 |
33,000 |
0.05% |
|
|
| 37 |
ROYAL BANK OF CANADA |
16,725 |
31,000 |
0.05% |
|
|
| 38 |
Airain ltd |
15,942 |
30,000 |
0.05% |
|
|
| 39 |
BLACKROCK ADVISORS LLC |
14,883 |
28,000 |
0.04% |
|
|
| 40 |
GUGGENHEIM CAPITAL LLC |
13,131 |
25,000 |
0.04% |
|
|
| 41 |
TFS CAPITAL LLC |
12,470 |
23,000 |
0.04% |
|
|
| 42 |
CITADEL ADVISORS LLC |
11,049 |
21,000 |
0.03% |
|
|
| 43 |
GROUP ONE TRADING LLC |
11,272 |
21,000 |
0.03% |
|
|
| 44 |
UBS Group AG |
11,430 |
21,000 |
0.03% |
|
|
| 45 |
MORGAN STANLEY |
10,359 |
19,000 |
0.03% |
|
|
| 46 |
BlackRock Investment Management, LLC |
10,006 |
19,000 |
0.03% |
|
|
| 47 |
Tower Research Capital LLC (TRC) |
3,439 |
6,000 |
0.01% |
|
|
| 48 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
2,233 |
4,000 |
0.01% |
|
|
| 49 |
PNC FINANCIAL SERVICES GROUP, INC. |
2,000 |
4,000 |
0.01% |
|
|
| 50 |
WASHINGTON TRUST BANK |
1,500 |
3,000 |
0.00% |
|
|
