| 1 |
First Eagle Investment Management, LLC |
10,912,733 |
13,750,000 |
25.52% |
|
|
| 2 |
Nantahala Capital Management, LLC |
9,333,541 |
11,760,000 |
21.83% |
|
|
| 3 |
BVF INC/IL |
7,400,128 |
9,324,000 |
17.31% |
|
|
| 4 |
VANGUARD GROUP INC |
2,975,694 |
3,750,000 |
6.96% |
|
|
| 5 |
NEA Management Company, LLC |
2,520,316 |
3,176,000 |
5.89% |
|
|
| 6 |
BlackRock Institutional Trust Company, N.A. |
2,030,407 |
2,558,000 |
4.75% |
|
|
| 7 |
RENAISSANCE TECHNOLOGIES LLC |
2,017,600 |
2,542,000 |
4.72% |
|
|
| 8 |
D. E. Shaw & Co., Inc. |
1,030,285 |
1,298,000 |
2.41% |
|
|
| 9 |
FMR LLC |
731,880 |
922,000 |
1.71% |
|
|
| 10 |
DAFNA Capital Management LLC |
668,735 |
843,000 |
1.56% |
|
|
| 11 |
EverPoint Asset Management, LLC |
449,770 |
567,000 |
1.05% |
|
|
| 12 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
360,193 |
454,000 |
0.84% |
|
|
| 13 |
GEODE CAPITAL MANAGEMENT, LLC |
322,528 |
406,000 |
0.75% |
|
|
| 14 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
225,900 |
285,000 |
0.53% |
|
|
| 15 |
State of New Jersey Common Pension Fund D |
223,774 |
282,000 |
0.52% |
|
|
| 16 |
NJ State Employees Deferred Compensation Plan |
190,000 |
239,000 |
0.44% |
|
|
| 17 |
STONERIDGE INVESTMENT PARTNERS LLC |
188,081 |
237,000 |
0.44% |
|
|
| 18 |
BlackRock Fund Advisors |
167,044 |
210,000 |
0.39% |
|
|
| 19 |
NORTHERN TRUST CORP |
145,716 |
184,000 |
0.34% |
|
|
| 20 |
DIMENSIONAL FUND ADVISORS LP |
106,746 |
134,000 |
0.25% |
|
|
| 21 |
NEW YORK STATE COMMON RETIREMENT FUND |
98,999 |
125,000 |
0.23% |
|
|
| 22 |
ALGERT GLOBAL LLC |
95,769 |
121,000 |
0.22% |
|
|
| 23 |
Connor, Clark & Lunn Investment Management Ltd. |
88,350 |
111,000 |
0.21% |
|
|
| 24 |
Bank of New York Mellon Corp |
69,581 |
87,000 |
0.16% |
|
|
| 25 |
PANAGORA ASSET MANAGEMENT INC |
55,170 |
70,000 |
0.13% |
|
|
| 26 |
Curbstone Financial Management Corp |
52,286 |
66,000 |
0.12% |
|
|
| 27 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
36,852 |
46,000 |
0.09% |
|
|
| 28 |
STATE STREET CORP |
33,095 |
41,000 |
0.08% |
|
|
| 29 |
GOLDMAN SACHS GROUP INC |
27,554 |
35,000 |
0.06% |
|
|
| 30 |
Virtu KCG Holdings LLC |
27,053 |
34,000 |
0.06% |
|
|
| 31 |
OPPENHEIMER & CO INC |
26,000 |
33,000 |
0.06% |
|
|
| 32 |
CITADEL ADVISORS LLC |
24,280 |
31,000 |
0.06% |
|
|
| 33 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
21,000 |
27,000 |
0.05% |
|
|
| 34 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
14,860 |
19,000 |
0.04% |
|
|
| 35 |
BLACKROCK ADVISORS LLC |
14,883 |
19,000 |
0.04% |
|
|
| 36 |
GUGGENHEIM CAPITAL LLC |
14,661 |
18,000 |
0.03% |
|
|
| 37 |
WOLVERINE TRADING LP /BD |
12,326 |
16,000 |
0.03% |
|
|
| 38 |
BlackRock Investment Management, LLC |
10,990 |
14,000 |
0.03% |
|
|
| 39 |
MORGAN STANLEY |
8,700 |
11,000 |
0.02% |
|
|
| 40 |
UBS Group AG |
6,000 |
8,000 |
0.01% |
|
|
| 41 |
Creative Planning |
5,000 |
6,000 |
0.01% |
|
|
| 42 |
ACROSPIRE INVESTMENT MANAGEMENT LLC |
4,100 |
5,000 |
0.01% |
|
|
| 43 |
ROYAL BANK OF CANADA |
4,225 |
5,000 |
0.01% |
|
|
| 44 |
Tower Research Capital LLC (TRC) |
4,108 |
5,000 |
0.01% |
|
|
| 45 |
JPMORGAN CHASE & CO |
2,180 |
3,000 |
0.01% |
|
|
| 46 |
Financial Architects, Inc |
500 |
1,000 |
0.00% |
|
|
| 47 |
Cubist Systematic Strategies, LLC |
323 |
0 |
0.00% |
|
|
| 48 |
CUTLER GROUP LLC / CA |
1 |
0 |
0.00% |
|
|
| 49 |
First Eagle Investment Management, LLC |
935,673 |
0 |
0.00% |
Call |
|
