| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 2,135,258 | 108,578,000 | 19.52% | ||
| 2 | Consonance Capital Management LP | 1,696,147 | 86,249,000 | 15.51% | ||
| 3 | EAGLE ASSET MANAGEMENT INC | 1,109,644 | 56,425,000 | 10.15% | ||
| 4 | Apex Capital Management | 586,701 | 29,834,000 | 5.36% | ||
| 5 | STATE STREET CORP | 521,774 | 26,528,000 | 4.77% | ||
| 6 | BlackRock Fund Advisors | 506,542 | 25,758,000 | 4.63% | ||
| 7 | GLENMEDE TRUST CO NA | 408,476 | 20,768,000 | 3.73% | ||
| 8 | VANGUARD GROUP INC | 263,446 | 13,396,000 | 2.41% | ||
| 9 | MARSHALL WACE, LLP | 194,728 | 9,902,000 | 1.78% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 168,859 | 8,586,000 | 1.54% | ||
| 11 | WALL STREET ASSOCIATES | 158,400 | 8,055,000 | 1.45% | ||
| 12 | APIS CAPITAL ADVISORS, LLC | 143,310 | 7,287,000 | 1.31% | ||
| 13 | GOLDMAN SACHS GROUP INC | 135,031 | 6,866,000 | 1.23% | ||
| 14 | INSIGHT CAPITAL RESEARCH & MANAGEMENT INC | 127,507 | 6,484,000 | 1.17% | ||
| 15 | MANAGED ACCOUNT ADVISORS LLC | 125,318 | 6,372,000 | 1.15% | ||
| 16 | NORTHERN TRUST CORP | 120,533 | 6,129,000 | 1.10% | ||
| 17 | Invesco Ltd. | 95,810 | 4,872,000 | 0.88% | ||
| 18 | LAZARD ASSET MANAGEMENT LLC | 93,715 | 4,765,000 | 0.86% | ||
| 19 | DEUTSCHE BANK AG\ | 78,734 | 4,003,000 | 0.72% | ||
| 20 | QS Investors, LLC | 77,513 | 3,942,000 | 0.71% | ||
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 75,923 | 3,860,000 | 0.69% | ||
| 22 | BAKER BROS. ADVISORS LP | 75,357 | 3,832,000 | 0.69% | ||
| 23 | Informed Momentum Co LLC | 74,915 | 3,809,000 | 0.68% | ||
| 24 | BAILARD, INC. | 74,500 | 3,788,000 | 0.68% | ||
| 25 | Bank of New York Mellon Corp | 72,389 | 3,682,000 | 0.66% | ||
| 26 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 70,822 | 3,602,000 | 0.65% | ||
| 27 | BENNETT LAWRENCE MANAGEMENT L L C/NY | 65,835 | 3,348,000 | 0.60% | ||
| 28 | CADENCE CAPITAL MANAGEMENT LLC | 65,191 | 3,315,000 | 0.60% | ||
| 29 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 65,027 | 3,307,000 | 0.59% | ||
| 30 | AQR CAPITAL MANAGEMENT LLC | 58,980 | 2,999,000 | 0.54% | ||
| 31 | TIAA CREF INVESTMENT MANAGEMENT LLC | 58,879 | 2,994,000 | 0.54% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 58,400 | 2,970,000 | 0.53% | Put | |
| 33 | NEW YORK STATE COMMON RETIREMENT FUND | 58,246 | 2,962,000 | 0.53% | ||
| 34 | BLACKROCK ADVISORS LLC | 57,586 | 2,928,000 | 0.53% | ||
| 35 | RUSSELL FRANK CO/ | 51,099 | 2,612,000 | 0.47% | ||
| 36 | WELLS FARGO & COMPANY/MN | 50,724 | 2,580,000 | 0.46% | ||
| 37 | B. Riley Wealth Advisors, Inc. | 6,462 | 2,452,000 | 0.44% | ||
| 38 | BlackRock Japan Co. Ltd | 44,735 | 2,275,000 | 0.41% | ||
| 39 | ACUTA CAPITAL PARTNERS, LLC | 44,528 | 2,264,000 | 0.41% | ||
| 40 | SENZAR ASSET MANAGEMENT, LLC | 44,117 | 2,243,000 | 0.40% | ||
| 41 | GUGGENHEIM CAPITAL LLC | 40,326 | 2,051,000 | 0.37% | ||
| 42 | SPHERA FUNDS MANAGEMENT LTD. | 40,000 | 2,034,000 | 0.37% | ||
| 43 | Candriam S.C.A. | 35,000 | 1,780,000 | 0.32% | ||
| 44 | Dai-ichi Life Holdings, Inc. | 30,358 | 1,544,000 | 0.28% | ||
| 45 | BlackRock Investment Management, LLC | 29,979 | 1,524,000 | 0.27% | ||
| 46 | AXA S.A. | 29,800 | 1,515,000 | 0.27% | ||
| 47 | NAVELLIER & ASSOCIATES INC | 28,759 | 1,462,000 | 0.26% | ||
| 48 | REGIONS FINANCIAL CORP | 28,167 | 1,432,000 | 0.26% | ||
| 49 | CITADEL ADVISORS LLC | 26,896 | 1,368,000 | 0.25% | ||
| 50 | TURNER INVESTMENTS LLC | 26,500 | 1,348,000 | 0.24% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
