| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BlackRock Fund Advisors | 1,293,604 | 34,423,000 | 9.83% | ||
| 2 | Krensavage Asset Management, LLC | 999,741 | 26,603,000 | 7.60% | ||
| 3 | GREAT POINT PARTNERS LLC | 790,000 | 21,022,000 | 6.01% | ||
| 4 | RENAISSANCE TECHNOLOGIES LLC | 701,400 | 18,664,000 | 5.33% | ||
| 5 | VANGUARD GROUP INC | 696,877 | 18,543,000 | 5.30% | ||
| 6 | SENZAR ASSET MANAGEMENT, LLC | 506,900 | 13,488,609 | 3.85% | ||
| 7 | Granahan Investment Management, LLC | 471,135 | 12,537,000 | 3.58% | ||
| 8 | FMR LLC | 411,815 | 10,958,000 | 3.13% | ||
| 9 | AJO, LP | 406,265 | 10,811,000 | 3.09% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 390,688 | 10,396,000 | 2.97% | ||
| 11 | ACADIAN ASSET MANAGEMENT LLC | 369,297 | 9,828,000 | 2.81% | ||
| 12 | STATE STREET CORP | 331,367 | 8,818,000 | 2.52% | ||
| 13 | Spark Investment Management LLC | 318,500 | 8,475,000 | 2.42% | ||
| 14 | Ghost Tree Capital, LLC | 250,000 | 6,653,000 | 1.90% | ||
| 15 | Matarin Capital Management, LLC | 246,848 | 6,568,626 | 1.88% | ||
| 16 | Candriam S.C.A. | 242,000 | 6,440,000 | 1.84% | ||
| 17 | ARMISTICE CAPITAL, LLC | 212,000 | 5,641,000 | 1.61% | ||
| 18 | Bank of New York Mellon Corp | 191,157 | 5,087,000 | 1.45% | ||
| 19 | McClain Value Management LLC | 183,086 | 4,872,000 | 1.39% | ||
| 20 | NORTHERN TRUST CORP | 182,817 | 4,864,000 | 1.39% | ||
| 21 | FIRST MANHATTAN CO. LLC. | 173,300 | 4,611,000 | 1.32% | ||
| 22 | DEUTSCHE BANK AG\ | 169,234 | 4,501,000 | 1.29% | ||
| 23 | MILLENNIUM MANAGEMENT LLC | 162,118 | 4,314,000 | 1.23% | ||
| 24 | HAYS ADVISORY LLC | 156,547 | 4,166,000 | 1.19% | ||
| 25 | SEIZERT CAPITAL PARTNERS, LLC | 152,190 | 4,050,000 | 1.16% | ||
| 26 | Numeric Investors LLC | 149,900 | 3,989,000 | 1.14% | ||
| 27 | JPMORGAN CHASE & CO | 138,975 | 3,698,000 | 1.06% | ||
| 28 | OXFORD ASSET MANAGEMENT LLP | 137,752 | 3,666,000 | 1.05% | ||
| 29 | ALLIANCEBERNSTEIN L.P. | 136,630 | 3,636,000 | 1.04% | ||
| 30 | GEODE CAPITAL MANAGEMENT, LLC | 126,148 | 3,356,000 | 0.96% | ||
| 31 | AMERIPRISE FINANCIAL INC | 107,965 | 2,873,000 | 0.82% | ||
| 32 | AQR CAPITAL MANAGEMENT LLC | 103,817 | 2,763,000 | 0.79% | ||
| 33 | PRINCIPAL FINANCIAL GROUP INC | 101,178 | 2,692,000 | 0.77% | ||
| 34 | QS Investors, LLC | 91,016 | 2,422,000 | 0.69% | ||
| 35 | D. E. Shaw & Co., Inc. | 87,339 | 2,324,000 | 0.66% | ||
| 36 | GSA CAPITAL PARTNERS LLP | 81,740 | 2,175,000 | 0.62% | ||
| 37 | PRUDENTIAL FINANCIAL INC | 81,404 | 2,166,000 | 0.62% | ||
| 38 | BAKER BROS. ADVISORS LP | 75,357 | 2,005,000 | 0.57% | ||
| 39 | BlackRock Investment Management, LLC | 72,626 | 1,933,000 | 0.55% | ||
| 40 | Gotham Asset Management, LLC | 68,514 | 1,823,000 | 0.52% | ||
| 41 | TWO SIGMA INVESTMENTS, LP | 67,348 | 1,792,000 | 0.51% | ||
| 42 | TIAA CREF INVESTMENT MANAGEMENT LLC | 63,315 | 1,685,000 | 0.48% | ||
| 43 | SECOR Capital Advisors, LP | 58,620 | 1,560,000 | 0.45% | ||
| 44 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 51,200 | 1,362,000 | 0.39% | ||
| 45 | Invesco Ltd. | 50,433 | 1,342,000 | 0.38% | ||
| 46 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 48,112 | 1,281,000 | 0.37% | ||
| 47 | Freedom Investment Management, Inc. | 44,871 | 1,194,000 | 0.34% | ||
| 48 | BLACKROCK ADVISORS LLC | 44,464 | 1,183,000 | 0.34% | ||
| 49 | VOYA INVESTMENT MANAGEMENT LLC | 43,962 | 1,170,000 | 0.33% | ||
| 50 | Asset Management One Co., Ltd. | 43,575 | 1,160,000 | 0.33% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
