| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Consonance Capital Management LP | 1,552,962 | 47,552,000 | 12.46% | ||
| 2 | FMR LLC | 1,359,435 | 41,626,000 | 10.91% | ||
| 3 | EAGLE ASSET MANAGEMENT INC | 1,127,238 | 34,516,000 | 9.04% | ||
| 4 | Apex Capital Management | 1,103,123 | 33,778,000 | 8.85% | ||
| 5 | STATE STREET CORP | 778,528 | 23,836,000 | 6.25% | ||
| 6 | Invesco Ltd. | 578,877 | 17,725,000 | 4.64% | ||
| 7 | BlackRock Fund Advisors | 526,625 | 16,125,000 | 4.23% | ||
| 8 | McClain Value Management LLC | 444,328 | 13,605,000 | 3.57% | ||
| 9 | Krensavage Asset Management, LLC | 424,016 | 12,983,000 | 3.40% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 324,645 | 9,941,000 | 2.60% | ||
| 11 | MANAGED ACCOUNT ADVISORS LLC | 314,511 | 9,630,000 | 2.52% | ||
| 12 | VANGUARD GROUP INC | 284,476 | 8,711,000 | 2.28% | ||
| 13 | MILLENNIUM MANAGEMENT LLC | 266,927 | 8,173,000 | 2.14% | ||
| 14 | Bank of New York Mellon Corp | 162,390 | 4,973,000 | 1.30% | ||
| 15 | SENZAR ASSET MANAGEMENT, LLC | 154,300 | 4,725,000 | 1.24% | ||
| 16 | WALL STREET ASSOCIATES | 151,800 | 4,648,000 | 1.22% | ||
| 17 | BALYASNY ASSET MANAGEMENT L.P. | 148,610 | 4,550,000 | 1.19% | ||
| 18 | Endurant Capital Management LP | 131,100 | 4,014,000 | 1.05% | ||
| 19 | PICTET ASSET MANAGEMENT LTD | 116,700 | 3,996,000 | 1.05% | ||
| 20 | APIS CAPITAL ADVISORS, LLC | 146,955 | 3,847,000 | 1.01% | ||
| 21 | MARSHALL WACE, LLP | 123,457 | 3,780,000 | 0.99% | ||
| 22 | NORTHERN TRUST CORP | 120,676 | 3,696,000 | 0.97% | ||
| 23 | NEW YORK STATE COMMON RETIREMENT FUND | 105,014 | 3,216,000 | 0.84% | ||
| 24 | BAILARD, INC. | 100,000 | 3,062,000 | 0.80% | ||
| 25 | GREAT POINT PARTNERS LLC | 100,000 | 3,062,000 | 0.80% | ||
| 26 | A.R.T. Advisors, LLC | 89,103 | 2,728,000 | 0.71% | ||
| 27 | GEODE CAPITAL MANAGEMENT, LLC | 85,331 | 2,612,000 | 0.68% | ||
| 28 | BLACKROCK ADVISORS LLC | 85,104 | 2,606,000 | 0.68% | ||
| 29 | QS Investors, LLC | 77,513 | 2,373,000 | 0.62% | ||
| 30 | BAKER BROS. ADVISORS LP | 75,357 | 2,307,000 | 0.60% | ||
| 31 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 74,696 | 2,288,000 | 0.60% | ||
| 32 | GSA CAPITAL PARTNERS LLP | 61,709 | 1,890,000 | 0.50% | ||
| 33 | TIAA CREF INVESTMENT MANAGEMENT LLC | 58,091 | 1,779,000 | 0.47% | ||
| 34 | BlackRock Japan Co. Ltd | 50,833 | 1,557,000 | 0.41% | ||
| 35 | Gotham Asset Management, LLC | 47,871 | 1,466,000 | 0.38% | ||
| 36 | JPMORGAN CHASE & CO | 45,508 | 1,393,000 | 0.37% | ||
| 37 | GUGGENHEIM CAPITAL LLC | 45,195 | 1,384,000 | 0.36% | ||
| 38 | GOLDMAN SACHS GROUP INC | 44,497 | 1,363,000 | 0.36% | ||
| 39 | AQR CAPITAL MANAGEMENT LLC | 41,462 | 1,270,000 | 0.33% | ||
| 40 | PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 38,400 | 1,176,000 | 0.31% | ||
| 41 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 37,600 | 1,151,000 | 0.30% | Put | |
| 42 | Municipal Employees' Retirement System of Michigan | 34,550 | 1,058,000 | 0.28% | ||
| 43 | WELLS FARGO & COMPANY/MN | 34,223 | 1,048,000 | 0.27% | ||
| 44 | WELLINGTON MANAGEMENT GROUP LLP | 33,973 | 1,040,000 | 0.27% | ||
| 45 | CREDIT SUISSE AG/ | 30,378 | 929,000 | 0.24% | ||
| 46 | AXA S.A. | 30,350 | 929,000 | 0.24% | ||
| 47 | BlackRock Investment Management, LLC | 30,342 | 929,000 | 0.24% | ||
| 48 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 29,918 | 916,000 | 0.24% | ||
| 49 | Airain ltd | 29,546 | 905,000 | 0.24% | ||
| 50 | CITADEL ADVISORS LLC | 28,639 | 877,000 | 0.23% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
