| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 6,678,000 | 312,998,000 | 10.20% | ||
| 2 | BlackRock Fund Advisors | 5,307,590 | 248,767,000 | 8.11% | ||
| 3 | VANGUARD GROUP INC | 4,804,707 | 225,197,000 | 7.34% | ||
| 4 | FRANKLIN RESOURCES INC | 3,349,284 | 156,980,000 | 5.12% | ||
| 5 | Invesco Ltd. | 3,333,612 | 156,246,000 | 5.09% | ||
| 6 | ARAVT GLOBAL LLC | 2,670,000 | 125,143,000 | 4.08% | ||
| 7 | STATE STREET CORP | 2,298,653 | 107,736,000 | 3.51% | ||
| 8 | Pennant Capital Management, LLC | 2,025,000 | 94,912,000 | 3.09% | ||
| 9 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 2,021,931 | 94,767,000 | 3.09% | ||
| 10 | Slate Path Capital LP | 1,935,000 | 90,693,000 | 2.96% | ||
| 11 | FMR LLC | 1,874,283 | 87,848,000 | 2.86% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 1,807,155 | 84,701,000 | 2.76% | ||
| 13 | DIMENSIONAL FUND ADVISORS LP | 1,603,880 | 75,173,000 | 2.45% | ||
| 14 | HIGHFIELDS CAPITAL MANAGEMENT LP | 1,400,000 | 65,618,000 | 2.14% | ||
| 15 | AMERIPRISE FINANCIAL INC | 1,220,628 | 57,211,000 | 1.86% | ||
| 16 | KORNITZER CAPITAL MANAGEMENT INC /KS | 1,056,680 | 49,527,000 | 1.61% | ||
| 17 | NORTHERN TRUST CORP | 989,623 | 46,384,000 | 1.51% | ||
| 18 | NWQ INVESTMENT MANAGEMENT COMPANY, LLC | 936,127 | 43,876,000 | 1.43% | ||
| 19 | MORGAN STANLEY | 869,312 | 40,744,000 | 1.33% | ||
| 20 | Neuberger Berman Group LLC | 819,619 | 38,416,000 | 1.25% | ||
| 21 | Hound Partners, LLC | 717,058 | 33,609,000 | 1.10% | ||
| 22 | Bank of New York Mellon Corp | 684,082 | 32,063,000 | 1.04% | ||
| 23 | JENNISON ASSOCIATES LLC | 673,653 | 31,574,000 | 1.03% | ||
| 24 | VICTORY CAPITAL MANAGEMENT INC | 638,478 | 29,926,000 | 0.98% | ||
| 25 | NORGES BANK | 607,139 | 28,457,000 | 0.93% | ||
| 26 | Penn Capital Management Company, LLC | 579,361 | 27,155,000 | 0.89% | ||
| 27 | PUTNAM INVESTMENTS LLC | 464,862 | 21,788,000 | 0.71% | ||
| 28 | GEODE CAPITAL MANAGEMENT, LLC | 447,204 | 20,959,000 | 0.68% | ||
| 29 | LOOMIS SAYLES & CO L P | 426,151 | 19,973,000 | 0.65% | ||
| 30 | PRINCIPAL FINANCIAL GROUP INC | 425,182 | 19,928,000 | 0.65% | ||
| 31 | Krensavage Asset Management, LLC | 410,944 | 19,261,000 | 0.63% | ||
| 32 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 409,381 | 19,187,687 | 0.63% | ||
| 33 | GOLDMAN SACHS GROUP INC | 382,544 | 17,930,000 | 0.58% | ||
| 34 | MILLENNIUM MANAGEMENT LLC | 357,326 | 16,748,000 | 0.55% | ||
| 35 | VOYA INVESTMENT MANAGEMENT LLC | 355,822 | 16,678,000 | 0.54% | ||
| 36 | Tekla Capital Management LLC | 344,683 | 16,155,000 | 0.53% | ||
| 37 | FEDERATED HERMES, INC. | 319,043 | 14,953,000 | 0.49% | ||
| 38 | PRUDENTIAL FINANCIAL INC | 294,781 | 13,816,000 | 0.45% | ||
| 39 | BANBURY PARTNERS LLC | 292,660 | 13,717,000 | 0.45% | ||
| 40 | TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 292,600 | 13,714,000 | 0.45% | ||
| 41 | BLUE JAY CAPITAL MANAGEMENT, LLC | 285,000 | 13,358,000 | 0.44% | ||
| 42 | TIAA CREF INVESTMENT MANAGEMENT LLC | 282,508 | 13,241,000 | 0.43% | ||
| 43 | NEW YORK STATE COMMON RETIREMENT FUND | 277,862 | 13,023,000 | 0.42% | ||
| 44 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 274,291 | 12,857,000 | 0.42% | ||
| 45 | ArrowMark Colorado Holdings LLC | 267,500 | 12,538,000 | 0.41% | ||
| 46 | BlackRock Investment Management, LLC | 252,201 | 11,821,000 | 0.39% | ||
| 47 | HUSSMAN STRATEGIC ADVISORS, INC. | 250,000 | 11,718,000 | 0.38% | ||
| 48 | TEACHERS ADVISORS, LLC | 245,094 | 11,488,000 | 0.37% | ||
| 49 | NEW AMSTERDAM PARTNERS LLC/NY | 224,754 | 10,534,000 | 0.34% | ||
| 50 | Tradewinds Global Investors, LLC | 210,687 | 9,874,000 | 0.32% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
