| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 6,776,100 | 216,971,000 | 10.29% | ||
| 2 | Hound Partners, LLC | 6,757,558 | 216,377,000 | 10.26% | ||
| 3 | BlackRock Fund Advisors | 5,612,082 | 179,699,000 | 8.52% | ||
| 4 | VANGUARD GROUP INC | 5,460,339 | 174,840,000 | 8.29% | ||
| 5 | Invesco Ltd. | 3,447,963 | 110,404,000 | 5.23% | ||
| 6 | ARAVT GLOBAL LLC | 3,071,878 | 98,362,000 | 4.66% | ||
| 7 | FRANKLIN RESOURCES INC | 2,316,406 | 74,173,000 | 3.52% | ||
| 8 | Pennant Capital Management, LLC | 2,083,074 | 66,700,000 | 3.16% | ||
| 9 | STATE STREET CORP | 1,740,986 | 55,742,000 | 2.64% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 1,721,824 | 55,133,000 | 2.61% | ||
| 11 | DIMENSIONAL FUND ADVISORS LP | 1,552,088 | 49,699,000 | 2.36% | ||
| 12 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,486,880 | 47,611,000 | 2.26% | ||
| 13 | Alyeska Investment Group, L.P. | 1,219,074 | 39,035,000 | 1.85% | ||
| 14 | NORTHERN TRUST CORP | 991,695 | 31,753,000 | 1.51% | ||
| 15 | VICTORY CAPITAL MANAGEMENT INC | 929,469 | 29,762,000 | 1.41% | ||
| 16 | AMERIPRISE FINANCIAL INC | 884,459 | 28,320,000 | 1.34% | ||
| 17 | Bank of New York Mellon Corp | 838,938 | 26,863,000 | 1.27% | ||
| 18 | GW&K Investment Management, LLC | 773,973 | 24,783,000 | 1.17% | ||
| 19 | PUTNAM INVESTMENTS LLC | 686,377 | 21,978,000 | 1.04% | ||
| 20 | MILLENNIUM MANAGEMENT LLC | 622,858 | 19,944,000 | 0.95% | ||
| 21 | Krensavage Asset Management, LLC | 587,882 | 18,824,000 | 0.89% | ||
| 22 | CITADEL ADVISORS LLC | 567,785 | 18,180,000 | 0.86% | ||
| 23 | ROYAL BANK OF CANADA | 555,374 | 17,783,000 | 0.84% | ||
| 24 | LOOMIS SAYLES & CO L P | 549,429 | 17,593,000 | 0.83% | ||
| 25 | NORGES BANK | 534,424 | 17,112,000 | 0.81% | ||
| 26 | TEACHERS ADVISORS, LLC | 512,311 | 16,404,000 | 0.78% | ||
| 27 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 508,650 | 16,287,000 | 0.77% | ||
| 28 | Penn Capital Management Company, LLC | 503,896 | 16,135,000 | 0.76% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 500,150 | 16,013,000 | 0.76% | ||
| 30 | Gotham Asset Management, LLC | 478,620 | 15,325,000 | 0.73% | ||
| 31 | PRINCIPAL FINANCIAL GROUP INC | 477,246 | 15,282,000 | 0.72% | ||
| 32 | KORNITZER CAPITAL MANAGEMENT INC /KS | 469,250 | 15,025,000 | 0.71% | ||
| 33 | EMERALD MUTUAL FUND ADVISERS TRUST | 440,919 | 14,118,000 | 0.67% | ||
| 34 | EMERALD ADVISERS, LLC | 391,106 | 12,523,000 | 0.59% | ||
| 35 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 335,263 | 10,736,000 | 0.51% | ||
| 36 | FMR LLC | 306,580 | 9,817,000 | 0.47% | ||
| 37 | BlackRock Investment Management, LLC | 278,093 | 8,905,000 | 0.42% | ||
| 38 | NEW AMSTERDAM PARTNERS LLC/NY | 276,784 | 8,863,000 | 0.42% | ||
| 39 | SG Americas Securities, LLC | 272,037 | 8,711,000 | 0.41% | ||
| 40 | DEUTSCHE BANK AG\ | 245,922 | 7,872,000 | 0.37% | ||
| 41 | TIAA CREF INVESTMENT MANAGEMENT LLC | 241,285 | 7,726,000 | 0.37% | ||
| 42 | OppenheimerFunds, Inc. | 240,997 | 7,717,000 | 0.37% | ||
| 43 | TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 240,000 | 7,685,000 | 0.36% | ||
| 44 | PANAGORA ASSET MANAGEMENT INC | 230,252 | 7,373,000 | 0.35% | ||
| 45 | Allianz Asset Management GmbH | 223,841 | 7,167,000 | 0.34% | ||
| 46 | GOLDMAN SACHS GROUP INC | 211,817 | 6,782,000 | 0.32% | ||
| 47 | Tradewinds Global Investors, LLC | 206,313 | 6,606,000 | 0.31% | ||
| 48 | NEW YORK STATE COMMON RETIREMENT FUND | 192,404 | 6,161,000 | 0.29% | ||
| 49 | NWQ INVESTMENT MANAGEMENT COMPANY, LLC | 190,660 | 6,104,933 | 0.29% | ||
| 50 | TWO SIGMA ADVISERS, LP | 175,649 | 5,624,000 | 0.27% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
