| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | GEODE CAPITAL MANAGEMENT, LLC | 125,793 | 2,201,000 | 0.79% | ||
| 52 | JPMORGAN CHASE & CO | 153,763 | 2,691,000 | 0.97% | ||
| 53 | Rhenman & Partners Asset Management AB | 155,000 | 2,713,000 | 0.97% | ||
| 54 | BAKER BROS. ADVISORS LP | 172,630 | 3,021,000 | 1.08% | ||
| 55 | FIL Ltd | 180,107 | 3,152,000 | 1.13% | ||
| 56 | INTERNATIONAL BIOTECHNOLOGY TRUST PLC | 185,234 | 3,236,000 | 1.16% | ||
| 57 | SPHERA FUNDS MANAGEMENT LTD. | 195,500 | 3,421,000 | 1.23% | ||
| 58 | NORTHERN TRUST CORP | 203,819 | 3,567,000 | 1.28% | ||
| 59 | Granite Point Capital Management, L.P. | 235,515 | 4,122,000 | 1.48% | ||
| 60 | PURA VIDA INVESTMENTS, LLC | 237,500 | 4,156,000 | 1.49% | ||
| 61 | STATE STREET CORP | 261,651 | 4,582,000 | 1.64% | ||
| 62 | Opaleye Management Inc. | 290,000 | 5,075,000 | 1.82% | ||
| 63 | MILLENNIUM MANAGEMENT LLC | 443,067 | 7,754,000 | 2.78% | ||
| 64 | EMERALD ADVISERS, LLC | 518,685 | 9,077,000 | 3.26% | ||
| 65 | ONTARIO TEACHERS PENSION PLAN BOARD | 547,683 | 9,584,000 | 3.44% | ||
| 66 | EMERALD MUTUAL FUND ADVISERS TRUST | 571,789 | 10,006,000 | 3.59% | ||
| 67 | ALLIANCEBERNSTEIN L.P. | 699,645 | 12,244,000 | 4.39% | ||
| 68 | VANGUARD GROUP INC | 716,419 | 12,537,000 | 4.50% | ||
| 69 | ARMISTICE CAPITAL, LLC | 864,000 | 15,120,000 | 5.42% | ||
| 70 | Brenner West Capital Advisors, LP | 1,191,282 | 20,847,000 | 7.48% | ||
| 71 | BlackRock Finance, Inc. | 1,300,429 | 22,757,000 | 8.16% | ||
| 72 | FMR LLC | 2,464,181 | 43,123,000 | 15.47% | ||
| 73 | GREAT POINT PARTNERS LLC | 2,601,351 | 45,524,000 | 16.33% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
