| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 834,811 | 8,665,000 | 49.76% | ||
| 2 | PERCEPTIVE ADVISORS LLC | 357,000 | 3,634,000 | 20.87% | ||
| 3 | BAKER BROS. ADVISORS LP | 142,000 | 1,446,000 | 8.30% | ||
| 4 | Knoll Capital Management, LLC | 135,800 | 1,382,000 | 7.94% | ||
| 5 | SPHERA FUNDS MANAGEMENT LTD. | 115,000 | 1,194,000 | 6.86% | ||
| 6 | DAFNA Capital Management LLC | 35,000 | 356,000 | 2.04% | ||
| 7 | GEODE CAPITAL MANAGEMENT, LLC | 22,558 | 234,000 | 1.34% | ||
| 8 | Spark Investment Management LLC | 22,700 | 230,000 | 1.32% | ||
| 9 | MORGAN STANLEY | 13,841 | 141,000 | 0.81% | ||
| 10 | Nicholas Investment Partners, LP | 8,333 | 85,000 | 0.49% | ||
| 11 | DEUTSCHE BANK AG\ | 2,530 | 25,000 | 0.14% | ||
| 12 | Tower Research Capital LLC (TRC) | 1,244 | 13,000 | 0.07% | ||
| 13 | Ironwood Financial, llc | 500 | 5,000 | 0.03% | ||
| 14 | BlackRock Investment Management, LLC | 269 | 3,000 | 0.02% | ||
| 15 | UBS Group AG | 209 | 2,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
