| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 1,437,811 | 9,748,000 | 32.47% | ||
| 2 | PERCEPTIVE ADVISORS LLC | 1,240,458 | 8,410,000 | 28.02% | ||
| 3 | DEERFIELD MANAGEMENT COMPANY, L.P. | 690,538 | 4,682,000 | 15.60% | ||
| 4 | SPHERA FUNDS MANAGEMENT LTD. | 238,500 | 1,617,000 | 5.39% | ||
| 5 | BAKER BROS. ADVISORS LP | 142,000 | 963,000 | 3.21% | ||
| 6 | Knoll Capital Management, LLC | 135,800 | 921,000 | 3.07% | ||
| 7 | VANGUARD GROUP INC | 118,340 | 802,000 | 2.67% | ||
| 8 | MILLENNIUM MANAGEMENT LLC | 110,024 | 746,000 | 2.49% | ||
| 9 | Weiss Multi-Strategy Advisers LLC | 76,000 | 515,000 | 1.72% | ||
| 10 | SABBY MANAGEMENT, LLC | 68,699 | 466,000 | 1.55% | ||
| 11 | BOXER CAPITAL, LLC | 63,146 | 428,000 | 1.43% | ||
| 12 | PURA VIDA INVESTMENTS, LLC | 57,500 | 390,000 | 1.30% | ||
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 22,558 | 152,000 | 0.51% | ||
| 14 | NORTHERN TRUST CORP | 12,286 | 83,000 | 0.28% | ||
| 15 | MORGAN STANLEY | 7,222 | 49,000 | 0.16% | ||
| 16 | BLACKROCK ADVISORS LLC | 2,978 | 20,000 | 0.07% | ||
| 17 | Vantage Investment Advisors, LLC | 2,000 | 14,000 | 0.05% | ||
| 18 | BlackRock Investment Management, LLC | 958 | 6,000 | 0.02% | ||
| 19 | BlackRock Fund Advisors | 781 | 5,000 | 0.02% | ||
| 20 | Tower Research Capital LLC (TRC) | 156 | 1,000 | 0.00% | ||
| 21 | UBS Group AG | 69 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
