| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 1,437,811 | 8,382,000 | 33.21% | ||
| 2 | PERCEPTIVE ADVISORS LLC | 957,193 | 5,580,000 | 22.11% | ||
| 3 | DEERFIELD MANAGEMENT COMPANY, L.P. | 690,538 | 4,026,000 | 15.95% | ||
| 4 | SPHERA FUNDS MANAGEMENT LTD. | 265,000 | 1,545,000 | 6.12% | ||
| 5 | BAKER BROS. ADVISORS LP | 142,000 | 828,000 | 3.28% | ||
| 6 | Knoll Capital Management, LLC | 135,800 | 792,000 | 3.14% | ||
| 7 | SABBY MANAGEMENT, LLC | 134,997 | 787,000 | 3.12% | ||
| 8 | MILLENNIUM MANAGEMENT LLC | 116,100 | 677,000 | 2.68% | ||
| 9 | VANGUARD GROUP INC | 107,270 | 626,000 | 2.48% | ||
| 10 | Weiss Multi-Strategy Advisers LLC | 76,000 | 443,000 | 1.76% | ||
| 11 | JPMORGAN CHASE & CO | 63,605 | 371,000 | 1.47% | ||
| 12 | Nicholas Investment Partners, LP | 63,666 | 371,000 | 1.47% | ||
| 13 | PURA VIDA INVESTMENTS, LLC | 57,500 | 335,000 | 1.33% | ||
| 14 | GEODE CAPITAL MANAGEMENT, LLC | 22,558 | 131,000 | 0.52% | ||
| 15 | MORGAN STANLEY | 20,496 | 119,000 | 0.47% | ||
| 16 | Spark Investment Management LLC | 18,400 | 105,000 | 0.42% | ||
| 17 | NORTHERN TRUST CORP | 12,286 | 71,000 | 0.28% | ||
| 18 | BLACKROCK ADVISORS LLC | 2,978 | 17,000 | 0.07% | ||
| 19 | Vantage Investment Advisors, LLC | 2,000 | 12,000 | 0.05% | ||
| 20 | UBS Group AG | 1,589 | 9,000 | 0.04% | ||
| 21 | Tower Research Capital LLC (TRC) | 1,305 | 8,000 | 0.03% | ||
| 22 | BlackRock Investment Management, LLC | 958 | 6,000 | 0.02% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
