| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PERCEPTIVE ADVISORS LLC | 1,940,458 | 11,041,000 | 30.60% | ||
| 2 | FMR LLC | 1,797,811 | 10,230,000 | 28.35% | ||
| 3 | AWM Investment Company, Inc. | 917,810 | 5,222,000 | 14.47% | ||
| 4 | SPHERA FUNDS MANAGEMENT LTD. | 368,500 | 2,097,000 | 5.81% | ||
| 5 | BOXER CAPITAL, LLC | 291,230 | 1,657,000 | 4.59% | ||
| 6 | DEERFIELD MANAGEMENT COMPANY, L.P. | 267,764 | 1,524,000 | 4.22% | ||
| 7 | BAKER BROS. ADVISORS LP | 142,000 | 808,000 | 2.24% | ||
| 8 | Knoll Capital Management, LLC | 135,800 | 773,000 | 2.14% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 130,500 | 743,000 | 2.06% | ||
| 10 | VANGUARD GROUP INC | 125,125 | 712,000 | 1.97% | ||
| 11 | PURA VIDA INVESTMENTS, LLC | 77,500 | 441,000 | 1.22% | ||
| 12 | Weiss Multi-Strategy Advisers LLC | 65,610 | 373,000 | 1.03% | ||
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 26,977 | 153,000 | 0.42% | ||
| 14 | BlackRock Fund Advisors | 20,630 | 117,000 | 0.32% | ||
| 15 | NORTHERN TRUST CORP | 12,366 | 70,000 | 0.19% | ||
| 16 | FNY Managed Accounts LLC | 5,000 | 28,450 | 0.08% | ||
| 17 | MORGAN STANLEY | 3,887 | 22,000 | 0.06% | ||
| 18 | BANK OF AMERICA CORP /DE/ | 3,254 | 18,000 | 0.05% | ||
| 19 | BLACKROCK ADVISORS LLC | 2,978 | 17,000 | 0.05% | ||
| 20 | DAFNA Capital Management LLC | 2,499 | 14,000 | 0.04% | ||
| 21 | Walleye Trading LLC | 1,400 | 8,000 | 0.02% | ||
| 22 | BlackRock Investment Management, LLC | 1,457 | 8,000 | 0.02% | ||
| 23 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 941 | 5,000 | 0.01% | ||
| 24 | WOLVERINE TRADING LP /BD | 207 | 1,139 | 0.00% | ||
| 25 | JPMORGAN CHASE & CO | 200 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
