| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Versant Venture Management, LLC | 2,208,210 | 15,015,828 | 16.84% | ||
| 2 | ProQuest Associates IV LLC | 1,962,720 | 13,346,000 | 14.96% | ||
| 3 | VICTORY CAPITAL MANAGEMENT INC | 1,937,554 | 13,175,000 | 14.77% | ||
| 4 | BVF INC/IL | 1,233,976 | 8,391,000 | 9.41% | ||
| 5 | BlackRock Finance, Inc. | 897,342 | 6,101,000 | 6.84% | ||
| 6 | FRANKLIN RESOURCES INC | 740,253 | 5,034,000 | 5.64% | ||
| 7 | FMR LLC | 445,152 | 3,027,000 | 3.39% | ||
| 8 | VANGUARD GROUP INC | 380,591 | 2,588,000 | 2.90% | ||
| 9 | Abingworth LLP | 352,300 | 2,378,000 | 2.67% | ||
| 10 | Cormorant Asset Management, LP | 337,000 | 2,292,000 | 2.57% | ||
| 11 | JPMORGAN CHASE & CO | 242,693 | 1,649,000 | 1.85% | ||
| 12 | STATE STREET CORP | 225,024 | 1,531,000 | 1.72% | ||
| 13 | Alyeska Investment Group, L.P. | 165,545 | 1,126,000 | 1.26% | ||
| 14 | MILLENNIUM MANAGEMENT LLC | 154,745 | 1,052,000 | 1.18% | ||
| 15 | BAKER BROS. ADVISORS LP | 148,937 | 1,013,000 | 1.14% | ||
| 16 | WELLS FARGO & COMPANY/MN | 148,887 | 1,012,000 | 1.13% | ||
| 17 | PANAGORA ASSET MANAGEMENT INC | 139,963 | 952,000 | 1.07% | ||
| 18 | NORTHERN TRUST CORP | 136,224 | 926,000 | 1.04% | ||
| 19 | DLD ASSET MANAGEMENT, LP | 120,100 | 814,000 | 0.91% | Call | |
| 20 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 115,000 | 782,000 | 0.88% | ||
| 21 | RENAISSANCE TECHNOLOGIES LLC | 111,740 | 760,000 | 0.85% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 103,298 | 702,000 | 0.79% | ||
| 23 | OXFORD ASSET MANAGEMENT LLP | 97,228 | 661,000 | 0.74% | ||
| 24 | Bain Capital Public Equity Management, LLC | 78,967 | 537,000 | 0.60% | ||
| 25 | Bank of New York Mellon Corp | 61,648 | 419,000 | 0.47% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 55,900 | 380,000 | 0.43% | Call | |
| 27 | Weiss Multi-Strategy Advisers LLC | 50,000 | 340,000 | 0.38% | ||
| 28 | DEUTSCHE BANK AG\ | 46,430 | 315,000 | 0.35% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 45,574 | 310,000 | 0.35% | ||
| 30 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 40,500 | 275,000 | 0.31% | Put | |
| 31 | D. E. Shaw & Co., Inc. | 34,662 | 236,000 | 0.26% | ||
| 32 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 27,874 | 190,000 | 0.21% | ||
| 33 | Trexquant Investment LP | 26,978 | 183,000 | 0.21% | ||
| 34 | Squarepoint Ops LLC | 22,983 | 156,000 | 0.17% | ||
| 35 | TEACHERS ADVISORS, LLC | 22,510 | 153,000 | 0.17% | ||
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 21,119 | 144,000 | 0.16% | ||
| 37 | MORGAN STANLEY | 18,298 | 124,000 | 0.14% | ||
| 38 | DIMENSIONAL FUND ADVISORS LP | 17,296 | 118,000 | 0.13% | ||
| 39 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 16,243 | 111,000 | 0.12% | ||
| 40 | BANK OF AMERICA CORP /DE/ | 15,246 | 104,000 | 0.12% | ||
| 41 | A.R.T. Advisors, LLC | 14,730 | 100,000 | 0.11% | ||
| 42 | RHUMBLINE ADVISERS | 12,798 | 87,000 | 0.10% | ||
| 43 | Connor, Clark & Lunn Investment Management Ltd. | 12,300 | 84,000 | 0.09% | ||
| 44 | Focused Wealth Management, Inc | 11,995 | 82,000 | 0.09% | ||
| 45 | CITADEL ADVISORS LLC | 11,500 | 78,000 | 0.09% | Put | |
| 46 | Nationwide Fund Advisors | 10,609 | 72,000 | 0.08% | ||
| 47 | NEW YORK STATE COMMON RETIREMENT FUND | 10,301 | 70,000 | 0.08% | ||
| 48 | AMERICAN INTERNATIONAL GROUP, INC. | 6,998 | 48,000 | 0.05% | ||
| 49 | ACADIAN ASSET MANAGEMENT LLC | 4,673 | 32,000 | 0.04% | ||
| 50 | WORTH VENTURE PARTNERS, LLC | 15,100 | 26,000 | 0.03% | Call |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
