| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | COLUMN GROUP L P | 3,161,942 | 97,072,000 | 33.02% | ||
| 2 | ProQuest Associates IV LLC | 2,695,757 | 82,975,000 | 28.23% | ||
| 3 | FMR LLC | 818,764 | 25,202,000 | 8.57% | ||
| 4 | PRICE T ROWE ASSOCIATES INC /MD/ | 749,141 | 23,059,000 | 7.84% | ||
| 5 | FRANKLIN RESOURCES INC | 738,026 | 22,716,000 | 7.73% | ||
| 6 | RS INVESTMENT MANAGEMENT CO LLC | 299,102 | 9,206,000 | 3.13% | ||
| 7 | JPMORGAN CHASE & CO | 229,450 | 7,063,000 | 2.40% | ||
| 8 | BlackRock Fund Advisors | 167,869 | 5,167,000 | 1.76% | ||
| 9 | Cormorant Asset Management, LP | 140,000 | 4,309,000 | 1.47% | ||
| 10 | STATE STREET CORP | 65,242 | 2,007,000 | 0.68% | ||
| 11 | VANGUARD GROUP INC | 60,180 | 1,853,000 | 0.63% | ||
| 12 | NORTHERN TRUST CORP | 54,571 | 1,679,000 | 0.57% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 47,766 | 1,470,000 | 0.50% | ||
| 14 | HAMILTON LANE ADVISORS LLC | 42,812 | 1,318,000 | 0.45% | ||
| 15 | Numeric Investors LLC | 37,012 | 1,139,000 | 0.39% | ||
| 16 | GOLDMAN SACHS GROUP INC | 36,652 | 1,128,000 | 0.38% | ||
| 17 | GEODE CAPITAL MANAGEMENT, LLC | 34,459 | 1,060,000 | 0.36% | ||
| 18 | SECTORAL ASSET MANAGEMENT INC | 21,181 | 652,000 | 0.22% | ||
| 19 | Bank of New York Mellon Corp | 18,240 | 561,000 | 0.19% | ||
| 20 | BlackRock Investment Management, LLC | 17,579 | 541,000 | 0.18% | ||
| 21 | Spark Investment Management LLC | 16,300 | 498,000 | 0.17% | ||
| 22 | TIAA CREF INVESTMENT MANAGEMENT LLC | 15,169 | 467,000 | 0.16% | ||
| 23 | TD ASSET MANAGEMENT INC | 14,400 | 443,000 | 0.15% | ||
| 24 | Nationwide Fund Advisors | 14,099 | 434,000 | 0.15% | ||
| 25 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 11,248 | 346,000 | 0.12% | ||
| 26 | MILLENNIUM MANAGEMENT LLC | 8,468 | 261,000 | 0.09% | ||
| 27 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 8,200 | 253,000 | 0.09% | ||
| 28 | MORGAN STANLEY | 8,111 | 250,000 | 0.09% | ||
| 29 | BLACKROCK ADVISORS LLC | 7,639 | 235,000 | 0.08% | ||
| 30 | TEACHERS ADVISORS, LLC | 5,679 | 175,000 | 0.06% | ||
| 31 | AMERICAN INTERNATIONAL GROUP, INC. | 3,830 | 117,887 | 0.04% | ||
| 32 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 2,807 | 86,000 | 0.03% | ||
| 33 | STRS OHIO | 2,100 | 65,000 | 0.02% | ||
| 34 | Focused Wealth Management, Inc | 1,634 | 50,000 | 0.02% | ||
| 35 | BlackRock Japan Co. Ltd | 1,045 | 32,000 | 0.01% | ||
| 36 | CITIGROUP INC | 1,044 | 32,000 | 0.01% | ||
| 37 | UBS Group AG | 832 | 26,000 | 0.01% | ||
| 38 | WELLS FARGO & COMPANY/MN | 383 | 12,000 | 0.00% | ||
| 39 | BARCLAYS PLC | 347 | 11,000 | 0.00% | ||
| 40 | PNC FINANCIAL SERVICES GROUP, INC. | 48 | 1,000 | 0.00% | ||
| 41 | DEUTSCHE BANK AG\ | 3 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
